Results 41 to 50 of about 329,930 (262)

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

Hypofractionated Radiotherapy Induces ISG15+MHC‐I+ Neutrophils to Augment Anti‐Tumor Immunity and Prime Immune Checkpoint Blockade Responses in Rectal Cancer

Advanced Science, EarlyView.
ABSTRACT Our previous clinical trials had demonstrated that neoadjuvant hypofractionated radiotherapy (HFRT) combined with immunotherapy yields promising clinical outcomes in locally advanced rectal cancer (LARC). However, this combined modality benefits only a subset of patients, highlighting the need to uncover the mechanisms underlying how ...
Lichao Liu, Haihong Wang, Mingjie Li, Qian Xu, Linlin Zheng, Chaoqun Han, Zhenwei Zou, Jinghua Ren, Xiaorong Dong, Peng Zhang, Kaixiong Tao, Zhenyu Lin, Tao Zhang   +12 more
wiley   +1 more source

Anàlisi del cercador múltiple Copernic 2001 Pro

BiD: Textos Universitaris de Biblioteconomia i Documentació, 2001
Anàlisi del cercador múltiple Copernic 2001 Pro, eina que transmet una equació de cerca a un conjunt de cercadors de manera simultània, en recupera les referències pertinents i les ordena segons el grau mitjà de rellevància obtingut de cadascun dels ...
Franganillo, Jorge, Figuerola, Teresa Maria   +1 more
doaj  

Weaving Entities into Relations: From Page Retrieval to Relation Mining on the Web [PDF]

, 2004
With its sheer amount of information, the Web is clearly an important frontier for data mining. While Web mining must start with content on the Web, there is no effective ``search-based'' mechanism to help sifting through the information on the Web.
Chang, Kevin Chen-Chuan, Cheng, Tao, Chuang, Shui-Lung, Davis, William, Kelley, Joseph M.   +4 more
core  

SocialSensor: sensing user generated input for improved media discovery and experience [PDF]

, 2012
SocialSensor will develop a new framework for enabling real-time multimedia indexing and search in the Social Web. The project moves beyond conventional text-based indexing and retrieval models by mining and aggregating user inputs and content over ...
Diplaris, S., Goker, A. S., Hacid, H., Klusch, M., Kompatsiaris, I., MacFarlane, A., Maknavicius, L., Papadopoulos, S., Spangenberg, J.   +8 more
core   +2 more sources

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple‐Negative Breast Cancer by Disrupting the Hippo‐YAP/TEAD4‐PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation

Advanced Science, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang, Wentao Si, Youxue Zhang, Jialin Liu, Huaixi Zhang, Yafei Li, Hongmeng Su, Wei Jiang, Zhishan Ding, Lihong Wang   +9 more
wiley   +1 more source

Análisis de consultas a un buscador y su aplicación a la jerarquización de páginas web

BiD: Textos Universitaris de Biblioteconomia i Documentació, 2003
Existen diversas fuentes de información en la web. Una de ellas es la información que deja el usuario mientras usa un buscador. Es posible utilizar esta información para complementar el resultado de algoritmos de jerarquización tradicionales, de manera ...
Baeza-Yates, Ricardo, Saint-Jean, Felipe
doaj  

Multistage BiCross encoder for multilingual access to COVID-19 health information.

PLoS ONE, 2021
The Coronavirus (COVID-19) pandemic has led to a rapidly growing 'infodemic' of health information online. This has motivated the need for accurate semantic search and retrieval of reliable COVID-19 information across millions of documents, in multiple ...
Iknoor Singh, Carolina Scarton, Kalina Bontcheva   +2 more
doaj   +1 more source

Evaluation of spoken document retrieval for historic speech collections [PDF]

, 2008
The re-use of spoken word audio collections maintained by audiovisual archives is severely hindered by their generally limited access. The CHoral project, which is part of the CATCH program funded by the Dutch Research Council, aims to provide users of ...
Heeren, W., Huijbregts, M., Jong, F. de, Ordelman, R., Werff, L. van der   +4 more
core   +1 more source

Learning Visual Features from Snapshots for Web Search

, 2017
When applying learning to rank algorithms to Web search, a large number of features are usually designed to capture the relevance signals. Most of these features are computed based on the extracted textual elements, link analysis, and user logs. However,
Cheng, Xueqi, Fan, Yixing, Guo, Jiafeng, Lan, Yanyan, Pang, Liang, Xu, Jun   +5 more
core   +1 more source