Results 131 to 140 of about 2,775,686 (184)
Advanced Science, EarlyView.This study demonstrates that the miRNA pathway plays a key role in the invasive growth of Alternanthera philoxeroides in aquatic habitats. Specifically, miR162 is critical for its invasive success, facilitating stem elongation and enhancing survival during submergence.
Qianqian Hu +8 more
wiley +1 more source
Advanced Science, EarlyView.Annexin A3 (ANXA3) plays an endogenous protective role in endothelial dysfunction in sepsis by stabilizing the actin cytoskeleton, modulating cell permeability, and inhibiting pATF2/CD62E inflammatory signaling. Abstract Increased endothelial permeability and a dysregulated inflammatory response play key roles in organ damage in sepsis.
Manyu Xing +4 more
wiley +1 more source
Advanced Science, EarlyView.The Semaphorin 3E (Sema3E)‐Plexin‐D1 pathway mediated by C/EBPα and C/EBPβ downstream of the luteinizing hormone (LH) surge plays important roles in the mouse preovulatory ovary. Timely activation and suppression of this pathway during the preovulatory stage are crucial for ovulation, corpus luteum formation, and proper angiogenesis.
Hanxue Zhang +11 more
wiley +1 more source
Advanced Science, EarlyView.The global energy demand drives the need for advanced energy‐efficient building solutions. While current polymeric‐shell microencapsulated PCMs show promise for thermal energy storage, their use in cementitious materials is challenged by poor shell strength and interfacial bonding. This study develops novel cement‐compatible microencapsulated PCM using
Sahand Rahemipoor +7 more
wiley +1 more source
Advanced Science, EarlyView.It is shown that obesity is associated with increases in hepatic METTL14 and m6A methylation of G6pc transcript. YTHDF1 and YTHDF3 bind to m6A‐marked G6pc mRNA to increase its synthesis. Hepatocyte‐specific deletion of Mettl14 decreases G6pc m6A methylation, G6pc biosynthesis, and G6pc‐mediated gluconeogenesis, alleviating glucose metabolic defects in ...
Qiantao Zheng +6 more
wiley +1 more source
Advanced Science, EarlyView.PRMT1 drives carboplatin resistance and tumor progression in head and neck squamous cell carcinoma (HNSCC) through a novel, methyltransferase‐independent mechanism. It recruits the SWI/SNF complex to activate IGF2BP2, promoting tumor growth and carboplatin resistance. PBX2 upregulates PRMT1, reinforcing this pathway. This study uncovers a non‐catalytic
Shixian Liu +22 more
wiley +1 more source
Advanced Science, EarlyView.A new amphipathic molecule, S416 is discovered, that locks the SARS‐CoV‐2 spike protein in its closed state, blocking viral entry. S416 acts as a molecular bolt, binding six sites: three between adjacent RBDs and three connecting NTDs to RBDs. This dual‐locking mechanism stiffens the spike structure and reduces its flexibility.
Shiliang Li +21 more
wiley +1 more source
Advanced Science, EarlyView.This study reveals that cytoplasmic PABPN1 is essential for mouse oocyte meiotic maturation by coordinating polyadenylation, translation, and degradation of maternal mRNAs. Pabpn1 knockout disrupts CDK1 activation, spindle formation, and chromosome alignment by impairing maturation‐promoting factor (MPF) regulation and BTG4‐mediated deadenylation ...
Xing‐Xing Dai +9 more
wiley +1 more source
Online Presence and Social Media: The JSPH Experience [PDF]
, 2010 Chosed, Lisa, MA +2 more
core +1 more source
Advanced Science, EarlyView.A multifunctional, edible, and hydrogel‐transformable probiotic powder is developed based on the “bacteria‐mediated bacterial eradication” strategy. By leveraging the targeted binding capability of L. reuteri to H. pylori, this approach achieves an integrated therapeutic effect, including bactericidality, anti‐inflammation, gastric mucosal repair, and ...
Yongkang Lai +9 more
wiley +1 more source