Results 51 to 60 of about 1,258,544 (313)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

OBITUARIES OF UKRAINIAN SOLDIERS IN REGIONAL AND NATIONAL ONLINE MEDIA

open access: yesІнтегровані комунікації
The Russian-Ukrainian war has actualized the genre of the obituary. Reports of military deaths began to be regularly published in periodicals, which makes it important to scientifically comprehend the genre modifications of the modern obituary, in ...
Ksenia Sizova, Vita Khmil-Chupryna
doaj   +1 more source

YouTube as a Source of Information on Epidural Steroid Injection

open access: yesJournal of Pain Research, 2021
Min Cheol Chang,1 Donghwi Park2 1Department of Physical Medicine and Rehabilitation, College of Medicine, Yeungnam University, Daegu, Republic of Korea; 2Department of Physical Medicine and Rehabilitation, Ulsan University Hospital, University of Ulsan ...
Chang MC, Park D
doaj  

The Homogeneity Process in the Online Media Agenda. A Comparative Analysis of Spanish and Foreign Online Media

open access: yesCommunication & Society (Formerly Comunicación y Sociedad), 2014
The research compares the thematic distribution between Spanish online media agenda and a sample of international mainstream online media on the headlines of their front pages.
Javier Odriozola-Chéné   +1 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Online Medya Okuryazarlığının Yetişkinler İçin Önemi “Online Haber Sitelerindeki Bannerlara Yönelik Bir İnceleme”

open access: yesOnline Academic Journal of Information Technology, 2013
Küreselleşme ve iletişim teknolojilerindeki gelişmeler, geleneksel anlamdaki okuryazarlık kavramının yeni uygulamaları da kapsayacak şekilde genişlemesine yol açmıştır. Doğrudan internete gönderme yapan ve sadece internet yoluyla karşı karşıya kaldığımız
Nilüfer Sezer, Nuray Yılmaz Sert
doaj   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

open access: yesNew Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

PENYELESAIAN SENGKETA BISNIS MELALUI ONLINE DISPUTE RESOLUTION DAN PEMBERLAKUANNYA DI INDONESIA

open access: yesMimbar Hukum, 2008
This paper is an attempt to discuss some issues concerning of business settlement via Online Dispute Resolution (ODR), Online Arbitrate Agreement, Online Arbitrate Procedure, Online Arbitrate Judgment, and examining the practice of the ODR in Indonesia ...
Bambang Sutiyoso
doaj  

REVIEW: Pactok: How the Pacific covers 'nius' on the internet

open access: yesPacific Journalism Review, 1996
Review of Pactok's Pacific Talk virtual library. Now a new venture by the Pactok organisation has created on-line access to locally produced news from the South-West Pacific region.
Christine Fogg
doaj   +1 more source

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