Results 141 to 150 of about 499,297 (296)

Dynamic Regulation of Endogenous Transcription Factor Hubs at Single‐Molecule Resolution

open access: yesAdvanced Science, EarlyView.
This study combines single‐molecule microscopy and genome editing to characterize the dynamic behaviors of endogenous oncofusion transcription factor EWS::FLI1 in Ewing sarcoma cells. EWS::FLI1 forms neomorphic hubs that dynamically assemble and dissolve. The hubs are regulated during mitosis, by RNA, and by specific chemicals.
Shawn Yoshida   +4 more
wiley   +1 more source

ANXA2‐mediated Phagocytosis Generates AR+ Macrophages to Confer Enzalutamide Resistance in Prostate Cancer

open access: yesAdvanced Science, EarlyView.
A novel resistance mechanism is mediated through phagocytosis of cancer cells by AR+ TAMs. This process, dependent on ANXA2, enables macrophages to acquire AR protein from engulfed tumor cells. The internalized AR translocates into the macrophage nucleus, where it binds directly to the IL‐6 promoter, augmenting IL‐6 transcription and secretion ...
Yong Luo   +13 more
wiley   +1 more source

Student recruitment survey 2024 [PDF]

open access: yes
This report sets out the findings of the annual ISE student recruitment survey. The survey was conducted in July 2024 and draws together the insights of 145 employers who recruited over 40,000 new student hires over the last year.
Lai, K. T   +3 more
core  

Project on Factors Affecting Recruitment and Selection Process in Bangladesh [PDF]

open access: yes, 2019
There is a supreme importance of recruitment and selection process in Human resource sector. Recruitment is become more and more important in every organization because of increased flexibility in the labor market.
Khatun, Mahbuba
core  

Dynamic Self‐Clickable Decellularized Matrix Hydrogels for Regulating Vascularity and Enhancing Muscle Regeneration

open access: yesAdvanced Science, EarlyView.
Dynamic decellularized hydrogels are prepared using bovine decellularized small intestine submucosa (SIS) norbornene (dSIS‐NB). Bovine dSIS contained significant amounts of disulfide‐rich fibrillin‐I, enabling ‘self‐clickable’ thiol‐norbornene gelation and spatiotemporal tuning of hydrogel physicochemical properties.
Van Thuy Duong   +4 more
wiley   +1 more source

Online Campus Recruitment System

open access: yes, 2018
The aim of this paper was to investigate the effective ways to maximize the role of recruitment agencies in Raipur. Bhilai was chosen as a location of this study. This qualitative study involved 7 informants from 3 categories: the recruitment agency operators, the employers, and the job applicants.
openaire   +2 more sources

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

open access: yesAdvanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu   +10 more
wiley   +1 more source

Using citation metrics as part of academic recruitment decisions leads to an increase in self-citations [PDF]

open access: yes, 2018
The use of citation metrics in academic hiring and promotion decisions was intended as a response to important and legitimate concerns over the meritocracy of recruitment procedures. However, evidence suggests that doing so distorts scientists' behaviour
Cattaneo, Mattia   +3 more
core  

Engineering Oncolytic Virus‐Armed Macrophages for Enhanced Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
ZIFOA‐M is engineered by conjugating oncolytic adenovirus‐loaded ZIF‐8 nanoparticles onto macrophage surfaces via bioorthogonal chemistry. Upon tumor infiltration, the platform releases OA to downregulate CD47/CD24 on tumor cells, restoring macrophage phagocytosis.
Jilong Wang   +10 more
wiley   +1 more source

Online recruitment for organizational knowledge management: a quantitative study [PDF]

open access: yes, 2017
The process of Recruitment and Selection of new employees has a growing influence on business results and, nowadays, the use of knowledge and information and communication technologies enables this process to be faster and more complete.
Silva, Susana   +2 more
core  

Home - About - Disclaimer - Privacy