Results 71 to 80 of about 1,833,837 (280)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Discourse analysis of online product reviews: A discussion of digital consumerism and culture

open access: yesCyberpsychology: Journal of Psychosocial Research on Cyberpspace, 2019
This study focuses on consumer interaction via online product reviews in digital markets by incorporating intercultural perspective. In doing so, this study explores the representation of digital consumerism, defined as development of consumer ...
Haseon Park, Joonghwa Lee
doaj   +1 more source

Investigating Online Reviews of Formalwear Rented Online: Information Generated by Female Consumers in Rent the Runway Sites [PDF]

open access: yes, 2014
With the explosive growth of e-commerce, consumer online reviews as a type of electronic word-of-mouth (eWOM) have become increasingly important. Because online reviews come from the consumer perspective, they are perceived to be more influential on ...
McKinney, Ellen   +2 more
core   +2 more sources

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Why Watching Movie Tweets Won't Tell the Whole Story?

open access: yes, 2012
Data from Online Social Networks (OSNs) are providing analysts with an unprecedented access to public opinion on elections, news, movies etc. However, caution must be taken to determine whether and how much of the opinion extracted from OSN user data is ...
Chiang, Mung   +2 more
core   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Textual Analysis for Online Reviews: A Polymerization Topic Sentiment Model

open access: yesIEEE Access, 2019
More and more e-commerce companies realize the importance of analyzing the online reviews of their products. It is believed that online review has a significant impact on the shaping product brand and sales promotion.
Lijuan Huang   +3 more
doaj   +1 more source

Merlot [PDF]

open access: yes, 2003
MERLOT is a community of educators in higher education who collaborate to develop and disseminate high quality online resources for faculty to incorporate into their courses.

core   +1 more source

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