Results 81 to 90 of about 12,927,233 (309)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Online therapy of addictive behaviors [PDF]

open access: yes, 2005
Clinicians working in the field of addictive behaviors cannot afford to ignore the Internet. Psychological advice, help, and treatment for addicts are no exceptions, with both counseling and psychotherapy entering the computer age. This paper reviews the
Griffiths, M
core  

Why Watching Movie Tweets Won't Tell the Whole Story?

open access: yes, 2012
Data from Online Social Networks (OSNs) are providing analysts with an unprecedented access to public opinion on elections, news, movies etc. However, caution must be taken to determine whether and how much of the opinion extracted from OSN user data is ...
Chiang, Mung   +2 more
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Environmental discourse in hotel online reviews: a big data analysis

open access: yesJournal of Sustainable Tourism, 2020
The purpose of this study is to investigate if there is a trend in online consumers’ environmental discourse, and whether online consumers’ environmental discourse differs across different types of online review platforms, i.e., transaction-based vs ...
Marcello M. Mariani, M. Borghi
semanticscholar   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Discourse analysis of online product reviews: A discussion of digital consumerism and culture

open access: yesCyberpsychology: Journal of Psychosocial Research on Cyberpspace, 2019
This study focuses on consumer interaction via online product reviews in digital markets by incorporating intercultural perspective. In doing so, this study explores the representation of digital consumerism, defined as development of consumer ...
Haseon Park, Joonghwa Lee
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Textual Analysis for Online Reviews: A Polymerization Topic Sentiment Model

open access: yesIEEE Access, 2019
More and more e-commerce companies realize the importance of analyzing the online reviews of their products. It is believed that online review has a significant impact on the shaping product brand and sales promotion.
Lijuan Huang   +3 more
doaj   +1 more source

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