Results 61 to 70 of about 138,067 (276)

SM2-Based Offline/Online Efficient Data Integrity Verification Scheme for Multiple Application Scenarios

Sensors, 2023
With the rapid development of cloud storage and cloud computing technology, users tend to store data in the cloud for more convenient services. In order to ensure the integrity of cloud data, scholars have proposed cloud data integrity verification ...
Xiuguang Li, Zhengge Yi, Ruifeng Li, Xu-An Wang, Hui Li, Xiaoyuan Yang   +5 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

UTSig: A Persian Offline Signature Dataset

, 2016
The pivotal role of datasets in signature verification systems motivates researchers to collect signature samples. Distinct characteristics of Persian signature demands for richer and culture-dependent offline signature datasets.
Araabi, Babak N., Fouladi, Kazim, Soleimani, Amir   +2 more
core   +1 more source

Offline Signature Verification Using Online Handwriting Registration [PDF]

2007 IEEE Conference on Computer Vision and Pattern Recognition, 2007
This paper proposes a novel framework for offline signature verification. Different from previous methods, our approach makes use of online handwriting instead of handwritten images for registration. The online registrations enable robust recovery of the writing trajectory from an input offline signature and thus allow effective shape matching between ...
Yu Qiao, Jianzhuang Liu, Xiaoou Tang
openaire   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Online Signature Biometrics for Mobile Devices

Sensors
This paper addresses issues concerning biometric authentication based on handwritten signatures. Our research aimed to check whether a handwritten signature acquired with a mobile device can effectively verify a user’s identity. We present a novel online
Katarzyna Roszczewska, Ewa Niewiadomska-Szynkiewicz   +1 more
doaj   +1 more source

Online Signature Verification: State of the art [PDF]

INTERNATIONAL JOURNAL OF COMPUTERS & TECHNOLOGY, 2005
online or Dynamic signature verification (DSV) is one of the most acceptable, intuitive, fast and cost effective tool for user authentication. DSV uses some dynamics like speed, pressure, directions, stroke length and pen-ups/pen-downs to verify the signer's identity. The state of the art in DSV is presented in this paper.
Ibrahim Elhenawy, Magdy Rashad, Omima Nomir, Kareem Ahmed   +3 more
openaire   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source