Results 191 to 200 of about 2,790,579 (282)

Intimate disclosure in online-only friendships predicts adolescents' depressive symptoms. [PDF]

J Res Adolesc
Kilic Z, Maheux AJ, Nesi J, Silk JS, Choukas-Bradley S.   +4 more
europepmc   +1 more source

Pancancer Fine‐Mapping of Mutational Intolerance Identifies CHEK1 as an Immunosuppressive Driver in Lung Adenocarcinoma

Advanced Science, EarlyView.
This study identifies mutation‐intolerant genes (MIGs), which are mutationally constrained in tumors despite normal‐tissue variability. Using miDriver, the authors pinpoint MIGs essential for tumor‐intrinsic fitness and immune evasion. Focusing on CHEK1, they show it drives tumor fitness and sculpts an immunosuppressive niche via the MIF–CD74 axis ...
Tao Wang, Hongyu Zhao, Xiaojie Sun, Yuqi Ding, Zhipeng Zhu, Xiaotong Yu, Rongyi Zhu, Dan Wang, Kailong Li, Yang Liu, Li‐Bin Wang, Xiaolu Zhao, Baojun Suo, Hongsen Bi, Peipei Zhang, Tong Liu, Fengbiao Mao   +16 more
wiley   +1 more source

The association between self-presentation on social network sites and interpersonal relationship satisfaction among high school students: the chain mediating role of self-esteem and self-identity. [PDF]

Front Psychol
Peng W, Shi G, Hu X, Zhuang H.
europepmc   +1 more source

In Situ Quantization with Memory‐Transistor Transfer Unit Based on Electrochemical Random‐Access Memory for Edge Applications

Advanced Science, EarlyView.
By combining ionic nonvolatile memories and transistors, this work proposes a compact synaptic unit to enable low‐precision neural network training. The design supports in situ weight quantization without extra programming and achieves accuracy comparable to ideal methods. This work obtains energy consumption advantage of 25.51× (ECRAM) and 4.84× (RRAM)
Zhen Yang, Yuxiang Yang, Baiqian Wang, Yaoyu Tao, Zelun Pan, Lei Cai, Teng Zhang, Longhao Yan, Xianbin Li, Yuchao Yang   +9 more
wiley   +1 more source

Promoter Hypermethylation‐Induced Silencing of FXYD1 Drives Breast Cancer Metastasis via DDX5‐Mediated Wnt/β‐Catenin Pathway Activation

Advanced Science, EarlyView.
This study identifies FXYD1 as an epigenetically silenced tumor suppressor in breast cancer. DNA methylation turns off the gene FXYD1 in breast cancer, and low levels predict worse outcomes. Restoring FXYD1 limits breast cancer cells proliferation and metastasis. In the nucleus, FXYD1 recruits the E3 ligase MAEA to K63‐ubiquitinate DDX5 for proteasomal
Ping Wen, Fanli Qu, Long Wang, Qing Shao, Sisi Li, Yang Qin, Dongping Jiang, Senmiao Zhang, Jiangdong Sui, Guanwen Wang, Ningning Zhang, Xiaohua Zeng   +11 more
wiley   +1 more source

Network structure shapes consensus dynamics through individual decisions. [PDF]

Proc Natl Acad Sci U S A
Priniski JH, Linford B, Hirschmann A, Venumuddala SK, Morstatter F, Rodriguez N, Brantingham PJ, Lu H.   +7 more
europepmc   +1 more source

Orbital Hybridization‐Mediated Decoupling of Electrocatalytic Functions for Paired CO2 Electrosynthesis

Advanced Science, EarlyView.
This study constructs a dual‐scale Ag‐based catalyst on CeO2 nanorods via a facet‐guided strategy. This catalyst can induce a cascaded orbital hybridization effect, which synergistically optimizes oxygen vacancy stability, CO desorption kinetics, and charge transfer efficiency.
Youjia Wang, Bochen Tian, Yuxin Tian, Wenchao Wang, Xin Ma, Yansheng Liu, Junwei Hou   +6 more
wiley   +1 more source

This article explains the secrecy paradox, but don't tell anyone! [PDF]

Front Psychol
Bergman DM.
europepmc   +1 more source

Social media and functional deterioration: indicators of problematic use in university students. [PDF]

Front Psychol
Carbonell-Colomer M, Marchena-Giráldez C, Bernabéu-Brotóns E.   +2 more
europepmc   +1 more source