Results 261 to 270 of about 248,560 (316)

Stage‐Specific H3K14 and H3K23 Succinylation Orchestrates Insect Metamorphosis and Oogenesis

Advanced Science, EarlyView.
Stage‐specific succinylation of histone H3 at lysine 14 and 23 differentially controls insect metamorphosis and oogenesis through distinct GPCR‐PKC signaling cascades, revealing an evolutionarily conserved epigenetic mechanism that coordinates key life‐history traits.
Yu‐Pu Jing, Lunjie Li, Libin Yang, Lin‐Jie Zhang, Qiang Yan, Ci Zhang, Zanrong Wen, Guangze Yu, Qian Li, Shutang Zhou   +9 more
wiley   +1 more source

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source

Neuromorphic Near‐Sensor and In‐Sensor Computing Enabled by Next‐Generation Material‐Based Sensors

Advanced Science, EarlyView.
This Review presents a structural framework that classifies neuromorphic sensing into near‐sensor and in‐sensor architectures, clarifying physical coupling between sensing and computation. The framework connects neural and synaptic device functions with recent advances in optical, mechanical, and chemical sensing, compares energy consumption and ...
Su Yeon Jung, Gwang Ya Kim, Sejin Kim, Hyunjong Seo, Se Gi Lee, Sang Min Won, Dongjoon Rhee, Joohoon Kang   +7 more
wiley   +1 more source

NFYB Integrates Hormonal Signals into Tissue Allometry by Promoting Protein Biosynthesis

Advanced Science, EarlyView.
In the American cockroach, NFYB acts as a spatiotemporin that translates distinct hormonal cues into tissue‐specific allometry. Juvenile hormone activates NFYB in the early fat body, while 20‐hydroxyecdysone induces it in late wing pads. NFYB then promotes protein biosynthesis via core translational machinery, driving differential growth across the ...
Fangfang Liu, Shiming Zhu, Sishi Xia, Xiaoshuai Zhang, Qin Li, Zhanquan Zeng, Yuqing Liu, Wanyin Liang, Guanyu Zhou, Erxia Du, Suning Liu, Sheng Li   +11 more
wiley   +1 more source

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Online social networks

IEEE Network, 2010
The popularity and complexity of online social networks (OSNs) continues to grow unabatedly with the most popular applications featuring hundreds of millions of active users. Ranging from social communities and discussion groups, to recommendation engines, tagging systems, mobile social networks, games, and virtual worlds, OSN applications have not ...
Michalis Faloutsos, Thomas Karagiannis, S. Moon   +2 more
openaire   +1 more source

On Social Synchrony in Online Social Networks

Proceedings of the 2017 ACM on Web Science Conference, 2017
In this work,we characterize a phenomenon called social synchrony that occurs in the online social networks. Social synchrony is a kind of collective social activity associated with some event where the number of people who participate in the activity first increases exponentially and then decreases exponentially.
Nirmal Kumar Sivaraman, Sakthi Balan Muthiah, Pushkal Agarwal, Lokesh Todwal   +3 more
openaire   +1 more source

Re-Socializing Online Social Networks

2010 IEEE/ACM Int'l Conference on Green Computing and Communications & Int'l Conference on Cyber, Physical and Social Computing, 2010
At present, the rapid development of Online Social Networks (OSN) has strong influence on our global community'scommunication patterns. This primarily manifests in an exponentially increasing number of users of Social Network Services(SNS) such as Face book or Twitter.
Michael Dürr, Martin Werner 0001, Marco Maier   +2 more
openaire   +1 more source

Online social support networks

International Review of Psychiatry, 2015
Peer support groups have a long history and have been shown to improve health outcomes. With the increasing familiarity with online social networks like Facebook and ubiquitous access to the Internet, online social support networks are becoming popular.
Neil, Mehta, Ashish, Atreja
openaire   +2 more sources