Results 101 to 110 of about 31,456,727 (314)

Computer-based library or computer-based learning? [PDF]

, 2010
Traditionally, libraries have played the role of repository of published information resources and, more recently, gateway to online subscription databases. The library online catalog and digital library interface serve an intermediary function to help
Khoo, S.G. Christopher
core  

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Transfer Function Models for the Localization of Seizure Onset Zone From Cortico-Cortical Evoked Potentials

Frontiers in Neurology, 2020
Surgical resection of the seizure onset zone (SOZ) could potentially lead to seizure-freedom in medically refractory epilepsy patients. However, localizing the SOZ can be a time consuming and tedious process involving visual inspection of intracranial ...
Golnoosh Kamali, Rachel June Smith, Mark Hays, Christopher Coogan, Nathan E. Crone, Joon Y. Kang, Sridevi V. Sarma, Sridevi V. Sarma   +7 more
doaj   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Transcultural Adaptation and Psychometric Evaluation of the Online Learning Self-Efficacy Scale among High School Seniors in Bandar Abbas City [PDF]

Interdisciplinary Journal of Virtual Learning in Medical Sciences
Background: Online education has become more popular in recent years. Nevertheless, students may face challenges in online courses that can influence their academic self-efficacy (ASF).
Habibollah Barani, Mohammad Reza Mohammadi Soleimani, Azita Amirfakhraei, Seyyed Abdul Wahab Samavi   +3 more
doaj   +1 more source

Review Summary Generation in Online Systems: Frameworks for Supervised and Unsupervised Scenarios

ACM Transactions on the Web, 2021
Wenjun Jiang, J. Chen, Xiaofei Ding, WU Jie, He Jiawei, Guojun Wang, Wenjun Jiang, J. Chen, Xiaofei Ding, Jie Wu   +9 more
semanticscholar   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Online Recommender System

International Journal for Research in Applied Science and Engineering Technology, 2021
As the size of the e-commerce market grows, the consequences of it are appearing throughout society.The business Environment of a company changes from a product center to a user center and introduces a recommendation system. However, the existing research has shown a limitation in deriving customized recommendation information to reflect the
openaire   +1 more source

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

FEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee, Ga Seul Lee, JinHan Kim, Kwang‐Hyun Park, Seong‐Ryung Go, Jeong Hee Moon, Eui‐Jeon Woo   +6 more
wiley   +1 more source

Ultimate Course Formula for How to Create and Sell Online Courses in 60 Days or Less: A Book Review [PDF]

Interdisciplinary Journal of Virtual Learning in Medical Sciences
Digital marketing and entrepreneurship are two of the main and crucial topics in the digital age, and almost every field of science is unaffected by this subject (1).
Leila Homayouni, Zahra Karimian
doaj   +1 more source