Results 91 to 100 of about 9,036,801 (325)
Frontiers in PsychologyIntroductionIn response to the COVID-19 pandemic, many mental health services had to adapt the way in which their services were delivered. Research exploring the effectiveness of remote therapy and interventions, especially within the bipolar disorder ...
Elizabeth Newton +10 more
doaj +1 more source
How accessible and acceptable are current GP referral mechanisms for IAPT for low-income patients? Lay and primary care perspectives [PDF]
, 2019 Background: Improving Access to Psychological Therapies (IAPT) constitutes a key element of England’s national mental health strategy. Accessing IAPT usually requires patients to self-refer on the advice of their GP.
Byng, R. +5 more
core +4 more sources
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Mismatch-based delayed thrombolysis: a meta-analysis [PDF]
, 2010 <p><b>Background and Purpose</b>: Clinical benefit from thrombolysis is reduced as stroke onset to treatment time increases. The use of "mismatch" imaging to identify patients for delayed treatment has face validity and has been used in
Anthony J. Furlan +6 more
core +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
The inflammatory process of gout and its treatment. [PDF]
, 2006 Gouty arthritis is a characteristically intense acute inflammatory reaction that erupts in response to articular deposits of monosodium urate (MSU) crystals.
Cronstein, Bruce N, Terkeltaub, Robert
core +2 more sources
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Frontiers in PsychiatryBackgroundThe area of social skills is broad, in theory and in practice. For social skills training, various clinical practices have been applied in group sessions, as have motivational resources such as role-playing games (RPGs).
Germano Henning +12 more
doaj +1 more source
Glucocorticoid therapy for adrenal insufficiency: nonadherence, concerns and dissatisfaction with information [PDF]
, 2016 Objective: Appropriate self‐management of glucocorticoid therapy (GC) is crucial for patients with adrenal insufficiency (AI). We aimed to describe patients’ self‐reported nonadherence to GC, evaluate perceived doubts about need for GC, concerns about ...
Carroll, P. +3 more
core +2 more sources