Results 121 to 130 of about 1,382,662 (294)

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Electronic and Magnetic Reconstructions in Manganite Superlattices

open access: yes, 2013
We investigate the electronic reconstruction at the interface between ferromagnetic metallic (FM) and antiferromagnetic insulating (AFI) manganites in superlattices using a two-orbital double-exchange model including superexchange interactions, Jahn ...
Kampf, Arno P., Pradhan, Kalpataru
core   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Atom transistor from the point of view of nonequilibrium dynamics

open access: yesNew Journal of Physics, 2015
We analyze the atom field-effect transistor scheme (Stickney et al 2007 Phys. Rev. A http://dx.doi.org/10.1103/PhysRevA.75.013608 75 http://dx.doi.org/10.1103/PhysRevA.75.013608 ) using the standard tools of quantum and classical nonequlilibrium dynamics.
Z Zhang, V Dunjko, M Olshanii
doaj   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

open access: yesFEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi   +7 more
wiley   +1 more source

The Fertility Pattern of Twins and the General Population Compared: Evidence from Danish Cohorts 1945-64 [PDF]

open access: yes
Twin studies provide an important possibility for demographers to analyze patterns of heritability and to estimate structural models with controls for endowments. These possibilities are increasingly used in the context of fertility and related behaviors.
Axel Skytthe   +3 more
core  

Spatio-Temporal Patterning in Primary Motor Cortex at Movement Onset [PDF]

open access: yes, 2017
Voluntary movement initiation involves the engagement of large populations of motor cortical neurons around movement onset. Despite knowledge of the temporal dynamics that lead to movement, the spatial structure of these dynamics across the cortical ...
Best, Matthew D.   +4 more
core   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Scleredema diabeticorum with unusual presentation and fatal outcome

open access: yesIndian Journal of Dermatology, 2008
We present a case of Scleredema Diabeticorum (SD) in a patient with diabetic neuropathy and restrictive respiratory disease with unusual skin lesion distribution.
Miyares Francisco   +4 more
doaj  

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