Results 111 to 120 of about 1,172,384 (295)

Program Evaluation Criteria Applied to Pay Equity in Ontario [PDF]

open access: yes
The Ontario experience with respect to pay equity is evaluated based0501nly on a set of program evaluation citeria. Such criteria are informative in their own right, but they also provide a systematic way of categorizing the issues that are involved in ...
Morley Gunderson, Paul Lanoie
core  

Call for Nominations for CHA Prizes and Awards [PDF]

open access: yes, 2020
The CHA announces its annual Macdonald, Ferguson and Neatby Prizes,Regional History Certificates of Merit and the first annual Ph.D.

core  

The Uppsala APP Mutation Promotes Wild‐Type Amyloid‐β Aggregation and Deposition In Vivo

open access: yesAdvanced Science, EarlyView.
We investigated in vivo cross‐seeding of amyloid‐β (Aβ) isoforms in transgenic mice co‐expressing wild‐typeAβ and the Uppsala‐mutant Aβ variant (AβUpp), lacking six central residues. Weleveraged MALDI‐MS imaging and hyperspectral microscopy to follow spatio‐temporalAβ deposition.
Junyue Ge   +14 more
wiley   +1 more source

Zapped: The High Cost of Ontario's Renewable Electricity Subsidies [PDF]

open access: yes
Ontario’s Green Energy and Green Economy Act subsidizes producers of renewable electricity by paying them far more for their output than the prevailing market price of electricity.
Benjamin Dachis, Jan Carr
core  

What are Canadian Labor Laws as They Relate to Leave Administration, Specifically Military, Disability, FMLA, Vacation and Bereavement? [PDF]

open access: yes, 2013
Question: What are Canadian labor laws as they relate to leave administration, specifically military, disability, FMLA, vacation and bereavement?
Calder, Jane, Macfarlane, Bryan
core   +1 more source

Postsynaptic Complexin Mediates Constitutive Exocytosis of Nicotinic Acetylcholine Receptor

open access: yesAdvanced Science, EarlyView.
Beyond its established presynaptic role, complexin is identified as a postsynaptic regulator of neurotransmitter receptor trafficking. By promoting constitutive and activity‐dependent exocytosis of nicotinic acetylcholine receptors, complexin controls spontaneous synaptic signaling at the C.
Ya Wang   +4 more
wiley   +1 more source

Policy Risk and Private Investment in Ontario’s Wind Power Sector [PDF]

open access: yes
Even though governments may adopt favourable regulatory policies for renewable power generation, their ability to encourage private sector investment depends also on the presence of regulatory governance institutions that provide credible long-term ...
Holburn, Guy L. F.   +2 more
core   +1 more source

Aboriginal Maple Syrup Values Report [PDF]

open access: yes, 2014
This report examines the values associated with maple syrup practices in Aboriginal contexts. It is based on fifteen interviews conducted with Aboriginal people who have knowledge of maple syrup practices in Ontario.
Chrétien, Annette
core   +1 more source

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

open access: yesAdvanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi   +7 more
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

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