Results 181 to 190 of about 124,617 (262)

Glucocorticoids modulate drug transporter function in human fetal brain endothelial cells

The Journal of Physiology, EarlyView.
Abstract figure legend P‐glycoprotein and breast cancer resistance protein are the most prominent drug transporters at the fetal blood–brain barrier. We isolated primary human fetal brain endothelial cells from early and mid‐gestation cerebral microvessels and exposed them to glucocorticoids cortisol and dexamethasone in vitro.
Nikola Ivanovski, Phetcharawan Lye, Enrrico Bloise, Stephen G. Matthews   +3 more
wiley   +1 more source

Ecologies of Risk: Malaria and Settler Landscape Transformation in 19th-Century Ontario. [PDF]

Am J Hum Biol
Cooke A, Brickley MB.
europepmc   +1 more source

SARS‐CoV‐2 targets mitochondria, exacerbating COVID‐19 pneumonia

The Journal of Physiology, EarlyView.
Abstract figure legend Following entry into airway epithelial cells (AECs), SARS‐CoV‐2 releases its single‐stranded RNA into the cytoplasm, where it is translated into viral proteins. Several of these viral proteins localize to mitochondria and interact with key mitochondrial components.
Danchen Wu, Asish Dasgupta, Jaskaran Singh Hora, Kuang‐Hueih Chen, Arinjay Banerjee, Stephen L. Archer   +5 more
wiley   +1 more source

COVID-19 immunisation among individuals with opioid use disorder in Ontario: a population-based cohort study. [PDF]

BMJ Public Health
Hanna M, Subic AM, Park AL, Wu F, Campbell DM, Leece P, Morrison L, Parsons J, Sellen K, Strike C, Gomes T, Orkin AM.   +11 more
europepmc   +1 more source

Associations between serum per- and polyfluoroalkyl substance concentrations and β-cell function and insulin resistance in adult females.

J Clin Endocrinol Metab
Palaniyandi J, Bruin JE, Fisher M, Borghese MM, Hoyeck MP, Panagiotopoulos C, Guay M, Ashley-Martin J.   +7 more
europepmc   +1 more source

Exploring disparities: a regional analysis of harm reduction supply distribution and opioid-related deaths across Ontario's Public Health Units. [PDF]

Harm Reduct J
Ledlie S, Scarfone K, Shearer D, Zurba N, Miskovic M, Munro C, Besharah J, Pinkerton S, Watts T, Gomes T.   +9 more
europepmc   +1 more source

Surveillance for <i>Ixodes scapularis</i> and <i>Ixodes pacificus</i> ticks and their associated pathogens in Canada, 2021. [PDF]

Can Commun Dis Rep
Ahmad S, Wafy G, Wilson C, Coatsworth H, Guillot C, Savage J, Leighton P, Goundar P, Morshed M, Buck P, Bourgeois AC, Gasmi S.   +11 more
europepmc   +1 more source

Data Resource Profile: Climate and Enteric Diseases Research Project (ClimED). [PDF]

Int J Epidemiol
Chua PLC, Madaniyazi L, Tobias A, Ng CFS, Phung VLH, Pan R, Hossain N, Abrutzky R, Carrasco Escobar G, Phung DT, Faruque ASG, Brown P, Stagliorio Coêlho MSZ, Saldiva PHN, Lavigne E, Salazar MA, Royé D, Jung CR, Tantrakarnapa K, Kliengchuay W, Scovronick N, Lynch V, Park J, Kim Y, Huang C, Semenza JC, Hales S, Hashizume M.   +27 more
europepmc   +1 more source

Optimal Reactive Balance Training Characteristics Poststroke: Secondary Analysis of a Clinical Trial

Physiotherapy Research International, Volume 31, Issue 3, July 2026.
ABSTRACT Background and Purpose Reactive balance training (RBT) has shown promise for enhancing reactive balance control and reducing falls poststroke. However, the optimal training parameters (e.g., intensity, duration) are unknown. This secondary analysis examined dose–response relationships between specific reactive balance training characteristics ...
Júlia O. Faria, Cynthia J. Danells, Elizabeth L. Inness, Avril Mansfield   +3 more
wiley   +1 more source

Rapid expansion of genotype D1.1 A(H5N1) influenza viruses in wild birds across North America during the 2024 migratory season. [PDF]

Nat Med
Harrington WN, Signore A, Kercher L, Giacinti JA, Kandeil A, Ahlstrom CA, Bevins S, Crossley B, Eure K, Fabrizio TP, Jeevan T, Lenoch J, Nolting JM, Rejmanek D, Stallknecht D, Bollinger T, Buck EJ, Carter D, Cohen BS, Dilione KE, Feddersen JC, Franks J, Goldsmith D, Highway CJ, Himsworth C, Holmes LP, Jardine C, Jahid MJ, Link P, Miller L, Nemeth NM, Owsiany M, Pybus M, Scott LC, Sharp C, Smith L, Steelman NJ, Stevens B, Berhane Y, Torchetti M, Ramey AM, Poulson R, Webby RJ.   +42 more
europepmc   +1 more source