Results 11 to 20 of about 41,565 (303)

Epigenetic program of ontogenesis and hyperfunction theory: reinterpreting the mechanisms of aging [PDF]

Frontiers in Aging
This paper presents a comparative analysis of the relationship between aging, the epigenetic program of ontogenesis, and the main postulates of the hyperfunction theory.
Lev Salnikov
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Dopamine receptors and key elements of the neurotrophins (BDNF, CDNF) expression patterns during critical periods of ontogenesis in the brain structures of mice with autism-like behavior (BTBR) or its absence (С57BL/6J)

Вавиловский журнал генетики и селекции
Analysis of the mechanisms underlying autism spectrum disorder (ASD) is an urgent task due to the everincreasing prevalence of this condition. The study of critical periods of neuroontogenesis is of interest, since the manifestation of ASD is often ...
P. D. Pravikova, M. A. Arssan, E. A. Zalivina, E. M. Kondaurova, E. A. Kulikova, I. I. Belokopytova, V. S. Naumenko   +6 more
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Whole transcriptome analysis of human erythropoietic cells during ontogenesis suggests a role of VEGFA gene as modulator of fetal hemoglobin and pharmacogenomic biomarker of treatment response to hydroxyurea in β-type hemoglobinopathy patients [PDF]

, 2017
Background: Human erythropoiesis is characterized by distinct gene expression profiles at various developmental stages. Previous studies suggest that fetal-to-adult hemoglobin switch is regulated by a complex mechanism, in which many key players still ...
Ali, Bassam R., Chondrou, Vasiliki, John, Anne, Kastrinou, Vlasia, Katsila, Theodora, Kolovos, Petros, Kourakli, Alexandra, Papachatzopoulou, Adamantia, Patrinos, George P., Pavlidaki, Alexia, Sgourou, Argyro, Symeonidis, Argiris   +11 more
core   +5 more sources

Modulation of Insulin Sensitivity of Hepatocytes by the Pharmacological Downregulation of Phospholipase D

International Journal of Endocrinology, 2015
Background. The role of phospholipase D (PLD) as a positive modulator of glucose uptake activation by insulin in muscle and adipose cells has been demonstrated. The role of PLD in the regulation of glucose metabolism by insulin in the primary hepatocytes
Nataliya A. Babenko, Vitalina S. Kharchenko   +1 more
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Accumulation of Secondary Metabolites of Rhodiola semenovii Boriss. In Situ in the Dynamics of Growth and Development

Metabolites, 2022
Rhodiola semenovii Boriss. (Regel and Herder) might be a promising replacement for the well-known but endangered Rhodiola rosea L. In this research, the metabolic profile of R. semenovii, including drug-active and stress-resistant components, was studied
Nina V. Terletskaya, Nazym K. Korbozova, Alexander E. Grazhdannikov, Gulnaz A. Seitimova, Nataliya D. Meduntseva, Nataliya O. Kudrina   +5 more
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Correlation with basic differentiation processes of neurons [PDF]

, 1991
The development of the spinal cord involves the proliferation of neurons, their migration to well-defined areas, fiber outgrowth and synapse formation. The present study was designed to correlate the spatiotemporal pattern of expression of synaptophysin,
Altman, Angulo, Bööj, Cabalka, Chun, Dennis, Devoto, Hsu, Jahn, Jahn, Jahn, Kanemitsu, Kaplan, Knaus, Leclerc, Leube, Ley, Lizardi, Lupa, Mandler, Narayanan, Nornes, Nornes, Oppenheim, Phelps, Ritchie, Ruppert, Saito, Sarthy, Schilling, Stein, Südhof, Thomas, Vaughn, Vaughn, Vaughn, Vaughn, Xue   +37 more
core   +2 more sources

Effect of Pre-/ Postnatal Hypoxia on Pyruvate Kinase in Rat Brain

International Journal of Secondary Metabolite, 2018
The effect of hypoxic hypoxia on the pyruvate kinase (PK) activity in the brain structures of white rats during ontogenesis in a comparative aspect has been studied.
Afag M Rashidova
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Tiny but Fatty: Lipids and Fatty Acids in the Daubed Shanny (Leptoclinus Maculatus), a Small Fish in Svalbard Waters

Biomolecules, 2020
The seasonal dynamic of lipids and their fatty acid constituents in the lipid sac and muscles of pelagic postlarval Leptoclinus maculatus, an ecologically important fish species in the Arctic food nets, in Kongsfjord, Svalbard waters was studied.
Svetlana A. Murzina, Svetlana N. Pekkoeva, Ekaterina A. Kondakova, Zinaida A. Nefedova, Kseniia A. Filippova, Nina N. Nemova, Alexei M. Orlov, Jorgen Berge, Stig Falk-Petersen   +8 more
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ТHE FORMATION OF STRUCTURES IN ONTOGENESIS, PROVIDING RESISTANCE TO METAPLASIA OF THE MUCOUS MEMBRANE OF THE LOWER THIRD OF HUMAN ESOPHAGUS

Креативная хирургия и онкология, 2017
Studied  features of  vascular-tissue ratios  of  mucous  membrane of  the  lower  third of the esophagus of human fetus and adult  persons as the basis of resistance of mucous membrane to metaplasia.
P. A. Gelashvili, V. N. Tokarev
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Ontogeny and Phylogeny of a New Hypotrichous Ciliate (Protista, Ciliophora), Metaurostylopsis alrasheidi n. sp., With Establishment of a New Genus Monourostylopsis n. gen.

Frontiers in Marine Science, 2020
In the present study, based on both morphologic and phylogenetic analyses, a new genus, Monourostylopsis n. gen., and new species, Metaurostylopsis alrasheidi n. sp. as well as a new combination, Monourostylopsis antarctica (Jung et al., 2011) n.
Wenya Song, Wenya Song, Yu Qiao, Jingyi Dong, William A. Bourland, Tengteng Zhang, Xiaotian Luo   +6 more
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