Results 171 to 180 of about 223,364 (391)

Computed tomographic investigation of a hatchling skull reveals ontogenetic changes in the dentition and occlusal surface morphology of Hadrosauridae (Dinosauria: Ornithischia)

open access: yesVertebrate Anatomy, Morphology, Palaeontology
CMN 8917 is a small, partial skull of a duck-billed dinosaur from the upper Campanian Dinosaur Park Formation in what is now Dinosaur Provincial Park, Alberta. It represents one of the few nestling-sized juvenile hadrosaurines known to date. Support for
Trystan Warnock-Juteau   +3 more
doaj   +1 more source

The Machine Conception of the Organism in Development and Evolution: A Critical Analysis [PDF]

open access: yes, 2014
This article critically examines one of the most prevalent metaphors in modern biology, namely the machine conception of the organism (MCO). Although the fundamental differences between organisms and machines make the MCO an inadequate metaphor for ...
Nicholson, Daniel J.
core  

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

Ontogeny of the Immune Response [PDF]

open access: bronze, 1966
Yoon Berm Kim   +2 more
openalex   +1 more source

Dendritic cells, monocytes and macrophages: a unified nomenclature based on ontogeny

open access: yesNature reviews. Immunology, 2014
M. Guilliams   +8 more
semanticscholar   +1 more source

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

open access: yesFEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri   +5 more
wiley   +1 more source

Anatomia e ontogênese da sâmara de Centrolobium tomentosum Guill. ex Benth. (Leguminosae: Papilionoideae)

open access: yesRodriguésia
RESUMO Dalbergieae é considerada uma tribo basal de Papilionoideae (Leguminosae) e apresenta grande variação carpológica; apesar disso, poucos trabalhos analisam detalhadamente os órgãos reprodutivos destas plantas. O presente estudo teve como objetivo a
Denise Maria Trombert Oliveira   +2 more
doaj   +1 more source

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