Results 291 to 300 of about 229,442 (394)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Bud Ontogeny in Nondefoliated and Defoliated Abies Balsamea at the Ultrastructural Level

, 1984
Buhari A. Oyofo
openalex   +1 more source

Comparative Postnatal Ontogeny of the Skull in Dromiciops gliroides (Marsupialia: Microbiotheriidae)

, 2004
Norberto P. Giannini, Fernando Abdala, David A. Flores   +2 more
openalex   +2 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

A CSF-cytokine code predicts macrophage response polarity and tumor outcomes

Vallelian F, Schaer D, Schulthess-Lutz N, Peterhans M, Baselgia L, Eschment M, Humar R.   +6 more
europepmc   +1 more source

Sexual Dimorphism on a Conserved Scaffold: Insights from the Floral Ontogeny of <i>Eurychorda</i> (Restionaceae: Poales). [PDF]

Plants (Basel)
Fomichev CI, Briggs BG, Sokoloff DD.
europepmc   +1 more source

Metabolic Depression in Cunner (Tautogolabrus adspersus) Is Influenced by Ontogeny, and Enhances Thermal Tolerance

, 2014
Nick I. Kelly, Abdullah Alzaid, Gordon W. Nash, A. Kurt Gamperl   +3 more
openalex   +2 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Unravelling the difference in craniofacial morphology of Yucatan miniature and standard pigs during postnatal ontogeny. [PDF]

Proc Biol Sci
Liang C, Qiu T, Marghoub A, Chathuranga DS, Buzi C, Profico A, Didziokas M, Baldwin MC, Pauws E, Liu ZJ, Rafferty KL, Herring SW, Moazen M.   +12 more
europepmc   +1 more source

The Ontogeny of White Leghorn Chicken (Gallus Domesticus) Blood Chemistry Changes in Response to Acute Exposure to 10% O2

Dane A. Crossley, Dr James Hicks
openalex   +1 more source