Results 101 to 110 of about 300,638 (342)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Modeling Industrial IoT Security Using Ontologies: A Systematic Review
IEEE Open Journal of the Communications SocietyThe significance of Industrial Internet of Things (IIoT) is undeniable, yet many critical industries remain hesitant to adopt it due to fundamental security, transparency and safety concerns.
Muhammad Aslam Jarwar +2 more
doaj +1 more source
Ontologies, Data Modeling, and TEI
Journal of the Text Encoding Initiative, 2015 This paper discusses the relationships between TEI and ontologies from the perspective of computer-based modeling, understood here as a way to establish meaning.
Øyvind Eide
doaj +1 more source
Higher-order Representation and Reasoning for Automated Ontology Evolution [PDF]
, 2010 : The GALILEO system aims at realising automated ontology evolution. This is necessary to enable intelligent agents to manipulate their own knowledge autonomously and thus reason and communicate effectively in open, dynamic digital environments ...
Bundy, Alan, Chan, M., Lehmann, J.
core
The generation of e-learning exercise problems from subject ontologies [PDF]
, 2006 The teaching/ learning of cognitive skills, such as problem-solving, is an important goal in most forms of education. In well-structured subject areas certain exercise problem types may be precisely described by means of machine-processable knowledge
Holohan, Edmond +3 more
core +2 more sources
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Linking Open Descriptions of Social Events (LODSE): A New Ontology for Social Event Classification
Information, 2018 The digital era has brought a number of significant changes in the world of communications. Although technological evolution has allowed the creation of new social event platforms to disclose events, it is still difficult to know what is happening around
Marcelo Rodrigues +2 more
doaj +1 more source
On the Succinctness of Query Rewriting over OWL 2 QL Ontologies with Shallow Chases [PDF]
, 2014 We investigate the size of first-order rewritings of conjunctive queries over OWL 2 QL ontologies of depth 1 and 2 by means of hypergraph programs computing Boolean functions. Both positive and negative results are obtained.
Kikot, Stanislav +3 more
core
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
A Distributed and Collaborative Intelligent System for Medical Diagnosis
Advances in Distributed Computing and Artificial Intelligence Journal, 2013 In this paper, we present a distributed collaborative system assisting physicians in diagnosis when processing medical images. This is a Web-based solution since the different participants and resources are on various sites.
Naoufel KHAYATI, Wided LEJOUAD-CHAARI
doaj +1 more source