Results 101 to 110 of about 275,690 (365)

Aber-OWL: a framework for ontology-based data access in biology [PDF]

open access: yes, 2014
Many ontologies have been developed in biology and these ontologies increasingly contain large volumes of formalized knowledge commonly expressed in the Web Ontology Language (OWL). Computational access to the knowledge contained within these ontologies relies on the use of automated reasoning.
arxiv   +1 more source

Semantic Network Analysis of Ontologies [PDF]

open access: yes, 2011
A key argument for modeling knowledge in ontologies is the easy re-use and re-engineering of the knowledge. However, current ontology engineering tools provide only basic functionalities for analyzing ontologies.
Hoser, Bettina   +4 more
core  

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

A Study on the Ontologies Developed Based on the Principles of Open Biomedical Ontologies Foundry

open access: yesپیاورد سلامت, 2019
Background and Aim: Ontologies facilitate data integration, exchange, searching and querying. Open Biomedical Ontologies (OBO) Foundry is a solution for creating reference ontologies.
Nader Alishan Karami   +3 more
doaj  

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

Working with Ontologies

open access: yes, 2016
Ontologies are powerful and popular tools to encode data in a structured format and manage knowledge. A large variety of existing ontologies offer users access to biomedical knowledge. This chapter contains a short theoretical background of ontologies and introduces two notable examples: The Gene Ontology and the ontology for Biological Pathways ...
Kramer, Frank, Beißbarth, Tim
openaire   +5 more sources

Structured peer-to-peer-based publication and sharing of ontologies to automatically process SPARQL query on a semantic sensor network

open access: yesInternational Journal of Distributed Sensor Networks, 2018
In recent years, semantic sensor networks are proposed, which apply ontologies to provide query capabilities and data access and allow users to express their needs at a conceptual level.
Huayou Si   +4 more
doaj   +1 more source

Semantic Mediation Model to Promote Improved Data Sharing Using Representation Learning in Heterogeneous Healthcare Service Environments

open access: yesApplied Sciences, 2019
Interoperability has become a major challenge for the development of integrated healthcare applications. This is mainly because of the reason that data is collected, processed, and managed using heterogeneous protocols, different data formats, and ...
Sajjad Ali, Ilyoung Chong
doaj   +1 more source

Hydrogen sulfide repairs testicular damage induced by heat stress in rats

open access: yesFEBS Open Bio, EarlyView.
Heat stress can cause testicular damage and affect fertility. We investigated the potential protective role of hydrogen sulfide (H2S) against heat stress‐induced testicular injury and observed that H2S donor NaHS can effectively restore testicular damage in rats by inhibiting inflammation and oxidative stress. Our results suggest that H2S might be used
Xinyu Guo   +6 more
wiley   +1 more source

Decoherence and Ontology [PDF]

open access: yes, 2019
This paper discusses the consequences of quantum mechanics for our understanding of physical reality, particularly regarding how classical concepts emerge from quantum laws; how common sense logic stands out as a special case of quantum logic applied to macroscopic objects; how causality and locality are found to be “provincial” consequences of quanta;
openaire   +4 more sources

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