Results 131 to 140 of about 300,638 (342)

An ontological analysis of some biological ontologies [PDF]

open access: yesFrontiers in Genetics, 2012
The functional importance of biological entities makes their understanding, analysis, and representation essential in modern biology. Arguably, semantic representation necessary for machine interoperability is a far more difficult task than syntactic representation, necessitating conceptual schema and ontologies for in-silico biological knowledge ...
openaire   +3 more sources

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Annotation of Heterogenous Media Using OntoMedia

open access: yes, 2006
While ontologies exist for the annotation of monomedia, interoperability between these schemes is an important issue. The OntoMedia ontology consists of a generic core, capable of representing a diverse range of media, as well as extension ontologies to ...
Jewell, Michael O   +3 more
core  

Ontology construction from online ontologies [PDF]

open access: yes, 2006
One of the main hurdles towards a wide endorsement of ontologies is the high cost of constructing them. Reuse of existing ontologies offers a much cheaper alternative than building new ones from scratch, yet tools to support such reuse are still in their infancy.
openaire   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Application and Role of Ontologies in Biomedical Information Retrieval Systems

open access: yesمجله انفورماتیک سلامت و زیست پزشکی, 2018
Introduction: Ontologies improve the quality of information retrieval (IR). Therefore, it is important to better know the process of ontology engineering and their application in IR.
Nader Alishan Karami   +3 more
doaj  

Can Ontology Inform Ontologies? [PDF]

open access: yes, 2009
Traditionally, since it was coined in the early 17th century by German school philosophy, the word "ontology" has been used to name a field of metaphysics as well as distinct metaphysical doctrines. Since the 1990s, the word "ontology" appears increasingly in information sciences, and likewise in fields that have been subjected to `informatisation ...
openaire   +1 more source

On Parfit’s Ontology [PDF]

open access: yesCanadian Journal of Philosophy, 2018
Parfit denies that the introduction of reasons into our ontology is costly for his theory. He puts forth two positions to help establish the claim: the Plural Senses View and the Argument from Empty Ontology. I argue that, first, the Plural Senses View for ‘exists’ can be expanded to allow for senses which undermine his ontological claims; second, the ...
openaire   +3 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Systematic Literature Review on Knowledge-Driven Approaches for Construction Safety Analysis and Accident Prevention

open access: yesBuildings
Due to its inherent complexities in the process and the dynamic interactions with external environmental factors, the construction industry is widely considered one of the most hazardous industries worldwide. With advancements in artificial intelligence (
Sonali Pandithawatta   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy