Disease association study of Autoimmune and autoinflammatory diseases by integrating multi-modal data and hierarchical ontologies. [PDF]
Liu A, Su Y, Zhu J, Li YY.
europepmc +1 more source
Ontological Physicalism and Property Pluralism: Why They are Incompatible [PDF]
Robert Francescotti
openalex +1 more source
Sugar Functionalized Collagen Material for Local Modulation of Innate Immunity
Modulation of the innate immune response at the implant site can significantly influence adaptive immunity. A mannose‐functionalized collagen patch, termed the Local Immunotuning Patch (LIP), has been designed to engage mannose receptors on antigen‐presenting cells while exhibiting antibacterial properties. LIP orchestrates complex immune pathways that
Francesca Taraballi+10 more
wiley +1 more source
ON THE VIEW TO THE NATURE AND ONTOLOGICAL SPACE IN THE JAPANESE MODERN LITERARY WORKS
Tetsuo Kidokoro
openalex +2 more sources
Enhanced Activities of OCT4 and SOX2 Promote Epigenetic Reprogramming by Shortening G1 Phase
Fusing the VP16 domain to OCT4 and SOX2 (OvSvK) enhances iPSC generation by activating downstream targets, including those regulating the cell cycle. This accelerates reprogramming by shortening the G1 phase and reducing H3K27me3 levels. Modulating Ccnd1, Cdkn2a, and Ccne1 improves efficiency, linking cell cycle to epigenetic remodeling.
Lin Guo+17 more
wiley +1 more source
VarGuideAtlas: a repository of variant interpretation guidelines. [PDF]
Costa M, García S A, Pastor O.
europepmc +1 more source
THE ONTOLOGY OF FICTIONAL OBJECTS WITH SPECIAL REFERENCE TO ROMAN INGARDEN
Mark Brzozowski
openalex +2 more sources
Genomic and Cis‐Regulatory Basis of a Plastic C3‐C4 Photosynthesis in Eleocharis Baldwinii
The sedge Eleocharis baldwinii remarkably switches between C3‐like and C4‐like photosynthesis in response to environmental conditions. Combining gap‐free genome assembly with single‐cell multi‐omics, this study uncovers how subgenome dominance and cell‐specific cis‐regulation enable C4 photosynthesis.
Lu Chen+11 more
wiley +1 more source
A Single-Cell Transcriptome Atlas of Epithelial Subpopulations in HPV-Positive and HPV-Negative Head and Neck Cancers. [PDF]
Bedard MC+10 more
europepmc +1 more source