Results 261 to 270 of about 276,244 (340)

Federated SPARQL query performance evaluation for exploring disease model mouse: combining gene expression, orthology, and disease knowledge graphs. [PDF]

BMC Med Inform Decis Mak
Kushida T, de Farias TM, Sima AC, Dessimoz C, Chiba H, Bastian FB, Masuya H.   +6 more
europepmc   +1 more source

M2 Macrophage‐Derived Extracellular Vesicles Reprogram Immature Neutrophils into Anxa1hi Neutrophils to Enhance Inflamed Bone Regeneration

Advanced Science, EarlyView.
This study reveals that M2‐EVs mitigate periodontitis‐induced bone resorption by modulating neutrophil fate. Single‐cell RNA sequencing identified an Anxa1hi neutrophil subpopulation with pro‐reparative properties. M2‐EVs disrupt neutrophil maturation, promoting this subpopulation through key reprogramming genes (Acvrl1, Fpr2). These findings highlight
Yufei Yao, Yijia Yin, Fangyuan Shuai, Waishan Lam, Tao Zhou, Yaxin Xie, Xuesong He, Xianglong Han   +7 more
wiley   +1 more source

MAD-Onto: an ontology design for mobile app development. [PDF]

Front Artif Intell
Abu-Salih B, Al-Tawil M, Khoury A, Al-Qudah DA, Abu Zaid I, Alabdale M, Azar D.   +6 more
europepmc   +1 more source

Comprehensive Characterization of Bihormonal Cells and Endocrine Cell Lineages in Mammalian Pancreatic Islets

Advanced Science, EarlyView.
This study integrates dual‐reporter genetics, imaging flow cytometry, and single‐cell sequencing to characterize rare bihormonal cells in mouse and human pancreatic islets. Gcg⁺Ins⁺ cells resemble α‐cells rather than transitional states. Cross‐species gene network analysis refines islet cell taxonomy and reveals human‐specific δ‐cell subtypes ...
Xin‐Xin Yu, Peng Peng, Yi‐Ning Wang, Mao‐Yang He, Shuang He, Chen‐Tao Jin, Liu Yang, Xi Wang, Jia‐Xi Zheng, Jie Gao, Cheng‐Ran Xu   +10 more
wiley   +1 more source

The BSSO Foundry: A community of practice for ontologies in the behavioural and social sciences. [PDF]

Wellcome Open Res
Hastings J, Zhang L, Schenk P, West R, Gehrke B, Hogan WR, Chorpita B, Johnston M, Marques MM, Webb TL, Baird HM, Crombez G, Michie S.   +12 more
europepmc   +1 more source

Mestizas and Cyborgs R Us: Ontological Nomadism and the Transnational Public Sphere in Kathy Acker's Empire of the Senseless

, 2000
Salah El Moncef
openalex   +1 more source

Synchrotron Radiation‐Based Tomography of an Entire Mouse Brain with Sub‐Micron Voxels: Augmenting Interactive Brain Atlases with Terabyte Data

Advanced Science, EarlyView.
Extended‐field acquisition enables sub‐micron X‐ray imaging of a full mouse brain. The 3.3‐teravoxel volume is reconstructed, registered to a reference atlas, and stored in hierarchical format to augment currently available atlases and improve resolution in the third dimension by an order of magnitude.
Mattia Humbel, Christine Tanner, Marta Girona Alarcón, Georg Schulz, Timm Weitkamp, Mario Scheel, Vartan Kurtcuoglu, Bert Müller, Griffin Rodgers   +8 more
wiley   +1 more source

Core reference ontology for individualized exercise prescription. [PDF]

Sci Data
Liu X, Yang Y, Zong H, Zhang K, Jiang M, Yu C, Chen Y, Bao T, Li D, Wang J, Tang T, Ren S, Ruso JM, Shen B.   +13 more
europepmc   +1 more source

Metabolic Stress‐Induced Choline Kinase α (CHKA) Activation in Endothelial Subpopulation Contributes to Diabetes‐Associated Microvascular Dysfunction

Advanced Science, EarlyView.
This study uncovers CHKA as a pivotal driver of vascular dysfunction in diabetic retinopathy and highlights its role in endothelial dysfunction through NAD⁺‐SIRT1‐Notch signaling. Single‐cell and functional analyses, combined with clinical and genetic validation, suggest CHKA as a promising therapeutic target for the prevention and treatment of ...
Ling Ren, Linyu Zhang, Yun Bai, Chang Huang, Xiaosa Li, Fanfei Ma, Wan Mu, Mudi Yao, Chang Jiang, Xiangjun Chen, Qin Jiang, Biao Yan   +11 more
wiley   +1 more source

Improving data sharing and knowledge transfer via the Neuroelectrophysiology Analysis Ontology (NEAO). [PDF]

Sci Data
Köhler CA, Grün S, Denker M.
europepmc   +1 more source