Results 261 to 270 of about 300,638 (342)

Decoding the Cellular Heterogeneity and Malignant Progression of Human Penile Squamous Cell Carcinoma by Single‐Cell RNA Sequencing

Advanced Science, EarlyView.
Single‐cell transcriptomic and functional analyses identify SEMA3C as a key regulator of tumor progression and tumor microenvironment remodeling in penile squamous cell carcinoma. SEMA3C promotes epithelial–mesenchymal transition, tumor growth, and invasion while shaping an immunosuppressive microenvironment, highlighting its potential as a prognostic ...
Xiheng Hu, Wensheng Shi, Liang Dong, Lingjuan Huang, Xiyuan Zhang, Yiting Feng, Jie Sun, Lanlan Liu, Teng Liu, Jun Fu, Bowen Zhong, Qihao Leng, Xiaohua Wu, Minfeng Chen, Lingfang Li, Yuan Li, Xin Jin, Long Wang, Jian Cao, Xin Li, Mingzhu Yin, Xiang Chen   +21 more
wiley   +1 more source

Building a framework for reproducibility: the case for standardized data reporting and metadata integration in zebrafish research.

Dis Model Mech
Ngu MS, Toro S, Burger A, Ang KC.
europepmc   +1 more source

Transdimensional Architecture of Consciousness: A Neurophenomenological and Ontological Investigation into the Nature of Reality in Oneiric States

Talmo Bellato
openalex   +1 more source

Semantic Web Query on E-Governance Data and Designing Ontology for Agriculture Domain

, 2013
Swaran Lata, Bhaskar Sinha, Ela Kumar, Somnath Chandra, Raghu Arora   +4 more
openalex   +1 more source

EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer

Advanced Science, EarlyView.
This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Chengyu Lv, Zihang Lin, Jiandong Sun, Yuhong Ye, Qibin Wu, Liangzhi Cai, Dabin Liu, Pengming Sun, Shie Wang   +8 more
wiley   +1 more source

Rendering knowledge graphs from aerospace dentistry processes for clinical decision support systems. [PDF]

Acta Astronaut
Amith MT, Vu J, Hou S, Sista V, Gong Y, Shah R, Neumann AC.   +6 more
europepmc   +1 more source

Annexin A13 Protects Against Acute Kidney Injury by Inactivating TGF‐β/Smad3 Signaling

Advanced Science, EarlyView.
ANXA13 is negatively regulated by Smad3 and exerts its protective role in AKI by inactivating TGF‐β/Smad3 signaling and Smad3‐p21 cell cycle arrest pathway through binding to TβRI, inhibiting the interaction between TβRI and TβRII, thereby suppressing TβRI phosporylation.
Jiaxiao Li, Chen Wu, Yuqi Zhu, Zicheng Liu, Wenjuan Yu, Andrew Lukwaro, Yu Zhong, Guoqiang Xie, Lili Zhou, Xiaoru Huang, Hui‐yao Lan, Junzhe Chen, Ying Tang   +12 more
wiley   +1 more source

Pre-Meta: priors-augmented retrieval for LLM-based metadata generation. [PDF]

Bioinformatics
Tinn P, Sørbø S, Jiang S, Voutetakis K, Giounis SM, Pilalis E, Papadodima O, Roman D.   +7 more
europepmc   +1 more source

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source

Leveraging knowledge for explainable AI in personalized cancer treatment: challenges and future directions. [PDF]

Front Digit Health
Daghir-Wojtkowiak E, Alfaro J, Mastromattei M, Palkowski A, Stares M, Roca-Umbert A, Krajnc A, Leoni R, Boland A, Nourbaksh A, Kallor A, Ducki C, Venditti D, Montesano C, Cipriani C, Faria D, Pflieger D, Zago E, Bardet E, Serrano F, Jeanneret F, Alouges D, Yin L, Coquelet E, Bacquet A, Bonchi F, Maiorino F, Torino F, Bedran G, Long JA, Balbi L, Guyon L, Bevilacqua L, Fiorelli M, Wagner MC, Reyes M, Roselli M, Silva MC, Waleron M, Dovrolis N, Filhol-Cochet O, Um IH, Wolflein G, Eugénio P, Bazelle P, Golnas P, Thorpe P, Bove P, Borole P, Bernardini R, Kumar R, Cicconi R, Kaltenbrunner S, Gravina S, Brezar S, Symeonides S, McGinn S, Nunes S, Hupp T, Gordienko Y, Varvaras D, Stirenko S, Xumerle L, Mariani S, Bouzit A, Gazut S, Poth H, Souliotis K, Katifelis H, Verzoni E, Procopio G, Schoch S, Lupiáñez-Villanueva F, Türk S, Barud K, Koroliouk D, Caubet J, Moreno Y, Descotes JL, Golna C, Guadalupi V, Garagnani P, Gazouli M, Deleuze JF, Folkvord F, Forgó N, Harrison DJ, Axelson H, Stellato A, Mattei M, Rajan A, Laird A, Battail C, Pesquita C, Zanzotto FM.   +94 more
europepmc   +1 more source