Results 271 to 280 of about 581,965 (380)
PRDM16 Reduces Cellular Senescence by Upregulating GSTM1
Cellular senescence drives aging and aging‐related organ disorders, yet PRDM16's role remains unexplored. This work uncovers that PRDM16 decreases significantly in aged organs, while its loss accelerates cellular senescence and aging‐related organ injury.
Qian Yuan +7 more
wiley +1 more source
Semantic Resources for Managing Knowledge in Battery Research. [PDF]
Clark S +7 more
europepmc +1 more source
THE ONTOLOGY OF FICTIONAL OBJECTS WITH SPECIAL REFERENCE TO ROMAN INGARDEN
Mark Brzozowski
openalex +2 more sources
Learning to map between ontologies on the semantic web
A. Doan +3 more
semanticscholar +1 more source
The Pathogenic Roles of Local Vitamin D Metabolism Defect in Valve Inflammation and Calcification
This study identifies the valvular interstitial cell populations responsible for valvular calcification induced by hyperphosphatemia and likely aging, uncovers local vitamin D metabolism defect‐induced inflammation as a critical pathogenic factor of calcific aortic valve disease, and highlights active vitamin D and ERK inhibitor as potential preventive
Ruichen Yang +10 more
wiley +1 more source
A review on knowledge and information extraction from PDF documents and storage approaches. [PDF]
Atagong SD +5 more
europepmc +1 more source
Developmental Hypoxia Enhances Kidney Organoid Complexity and Maturity
The current bottleneck in metanephric mesenchyme (MM)‐derived nephron organoid development is the absence of a connected network of collecting ducts (CD) derived from the ureteric bud (UB). To address this limitation, this study proposes a hypoxia‐based differentiation method that mimics the natural renal developmental environment, enabling the ...
Hyeonji Lim +6 more
wiley +1 more source
A Prion‐Like Domain in EBV EBNA1 Promotes Phase Separation and Enables SRRM1 Splicing
This study discoveries that EBV EBNA1 behaves as a prion‐like protein, verified using cell‐based assays and the Saccharomyces cerevisiae Sup35p prion identification system. The prion‐like domain of EBNA1 drives liquid–liquid phase separation. EBNA1 interacts with the splicing factor SRSF1 to regulate the expression of the SRRM1 splicing isoforms ...
Xiaoyue Zhang +17 more
wiley +1 more source

