Results 81 to 90 of about 514,391 (335)

The role of ontologies in biological and biomedical research: a functional perspective

Briefings Bioinform., 2015
Ontologies are widely used in biological and biomedical research. Their success lies in their combination of four main features present in almost all ontologies: provision of standard identifiers for classes and relations that represent the phenomena ...
R. Hoehndorf, P. Schofield, G. Gkoutos
semanticscholar   +1 more source

Using Cross-Lingual Explicit Semantic Analysis for Improving Ontology Translation [PDF]

, 2012
Semantic Web aims to allow machines to make inferences using the explicit conceptualisations contained in ontologies. By pointing to ontologies, Semantic Web-based applications are able to inter-operate and share common information easily.
Aggarwal, Nitish, Asooja, Kartik, Gracia, Jorge, Gómez-Pérez, A.   +3 more
core   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Ontology or Ontologies?

, 2015
En recientes décadas se ha observado un renovado interés por algunos de los temas clásicos de la ontología, desde áreas de conocimiento externas a la filosofía, sin embargo, este renacimiento ontológico ha «estimulado» una multiplicidad y diversidad de teorías y concepciones «ontológicas» que ha dado como consecuencia una proliferación de «ontologías ...
openaire   +2 more sources

Ontology localization

Proceedings of the fifth international conference on Knowledge capture, 2009
nternational organizations (e.g., FAO1 , WHO2 , etc.) are increasingly expressing the need for multilingual ontologies for di®erent purposes, e.g., ontology-based multilingual machine translation, multilingual informa- tion retrieval. However, most of the ontologies built so far have mainly English or another natural language as basis.
Espinoza Mejía, Mauricio, Montiel Ponsoda, Elena, Gómez-Pérez, A.   +2 more
openaire   +2 more sources

Conceptual modelling and the quality of ontologies: A comparison between object-role modelling and the object paradigm [PDF]

, 2010
Ontologies are key enablers for sharing precise and machine-understandable semantics among different applications and parties. Yet, for ontologies to meet these expectations, their quality must be of a good standard.
Al-Asswad, MM, Al-Debei, MM, de Cesare, S, Lycett, M   +3 more
core  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Semantic Mediation Model to Promote Improved Data Sharing Using Representation Learning in Heterogeneous Healthcare Service Environments

Applied Sciences, 2019
Interoperability has become a major challenge for the development of integrated healthcare applications. This is mainly because of the reason that data is collected, processed, and managed using heterogeneous protocols, different data formats, and ...
Sajjad Ali, Ilyoung Chong
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

A Survey on Ontologies’ Adaptability and Interoperability

Cybernetics and Information Technologies
Interoperability issues emerge due to differences in the sizes and expressive powers of ontologies. Although ontologies are expressive, they tend to lack flexibility. Research shows that specialized ontologies are not merely advantageous for a particular
Dahir Sarah, Qadi Abderrahim El
doaj   +1 more source