Results 81 to 90 of about 300,638 (342)
Ontology-based domain modelling for consistent content change management [PDF]
, 2010 Ontology-based modelling of multi-formatted software application content is a challenging area in content management. When the number of software content unit is huge and in continuous process of change, content change management is important.
Abgaz, Yalemisew +2 more
core +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
A Study on the Ontologies Developed Based on the Principles of Open Biomedical Ontologies Foundry
پیاورد سلامت, 2019 Background and Aim: Ontologies facilitate data integration, exchange, searching and querying. Open Biomedical Ontologies (OBO) Foundry is a solution for creating reference ontologies.
Nader Alishan Karami +3 more
doaj
Building a biomedical ontology recommender web service
Journal of Biomedical Semantics, 2010 Background Researchers in biomedical informatics use ontologies and terminologies to annotate their data in order to facilitate data integration and translational discoveries.
Jonquet Clement +2 more
doaj +1 more source
Automating the Provisioning and Configuration of Devices in the Internet of Things
Complex Systems Informatics and Modeling Quarterly, 2016 The Internet of Things benefits from an increasing number of interconnected technical devices. This has led to the existence of so-called smart environments, which encompass one or more devices sensing, acting, and automatically performing different ...
Pascal Hirmer +5 more
doaj +1 more source
Iconarp International J. of Architecture and Planning, 2017 Debates about “being” and “existence” have continued uninterruptedly since ancient times in accordance with the evolution of philosophical thinking albeit at various levels of intensity. “Spatial Planning” which had not constitute a problem area for mankind until the industrial revolution, was linked to “ontology” either.
openaire +7 more sources
The African wildlife ontology tutorial ontologies [PDF]
Journal of Biomedical Semantics, 2020 Abstract Background Most tutorial ontologies focus on illustrating one aspect of ontology development, notably language features and automated reasoners, but ignore ontology development factors, such as emergent modelling guidelines and ontological principles. Yet, novices replicate examples from the exercise they carry out. Not providing good examples
openaire +4 more sources
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
A Survey on Ontologies’ Adaptability and Interoperability
Cybernetics and Information TechnologiesInteroperability issues emerge due to differences in the sizes and expressive powers of ontologies. Although ontologies are expressive, they tend to lack flexibility. Research shows that specialized ontologies are not merely advantageous for a particular
Dahir Sarah, Qadi Abderrahim El
doaj +1 more source