Results 261 to 270 of about 1,266,792 (389)

Improved detection of overrepresentation of Gene-Ontology annotations with parent–child analysis [PDF]

open access: hybrid, 2007
Steffen Großmann   +3 more
openalex   +1 more source

Deacetylation of ACLY Mediates RNA M6A‐Modification of NOXA and Promotes Chemoresistance of Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
This study investigates the deacetylation of ACLY at K978 acts as a novel risk in colorectal cancer chemoresistance. The deacetylation of K978 induces ACLY relocation to the nucleus and promotes its binding to RBM15, a m6A methylation modification “writer”.
Jun Wen   +8 more
wiley   +1 more source

Semantic web ontology for structured knowledge representation and clinical decision support in eye diseases. [PDF]

open access: yesSci Rep
Anjum F   +7 more
europepmc   +1 more source

Arabidopsis TRB Proteins Form Two Closely Related Complexes to Mediate H3K4me3 Demethylation and Transcriptional Repression

open access: yesAdvanced Science, EarlyView.
This study reveals that Arabidopsis telomere repeat binding proteins (TRBs) form two closely related complexes. These complexes mediate H3K4me3 demethylation and transcriptional repression through a positive feedback loop and cooperate with PEAT and PRC2 complexes to regulate multiple histone modifications and gene expression across the genome ...
Qi Wang   +7 more
wiley   +1 more source

Neuro-symbolic AI for auditable cognitive information extraction from medical reports. [PDF]

open access: yesCommun Med (Lond)
Prenosil GA   +8 more
europepmc   +1 more source

Ontology paper: The SSN ontology of the W3C semantic sensor network incubator group

open access: yes, 2012
M. Compton   +21 more
semanticscholar   +1 more source

Single Cell and Spatial Transcriptomics Define a Proinflammatory and Profibrotic Niche After Kidney Injury

open access: yesAdvanced Science, EarlyView.
By integrating single‐cell RNA sequencing and spatial transcriptomics, tenascin C (TNC) is unveiled as a central organizer of the proinflammatory and profibrotic niche in kidney fibrosis. TNC promotes macrophage activation through TLR4/NF‐κB signaling, leading to renal inflammation and fibrosis.
Li Li   +14 more
wiley   +1 more source

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