Results 271 to 280 of about 1,189,057 (413)
STAR/mmCIF: An ontology for macromolecular structure [PDF]
, 2000 John D. Westbrook, Philip E. Bourne
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Targeting miRNA‐1a and miRNA‐15b: A Novel Combinatorial Strategy to Drive Adult Cardiac Regeneration
Advanced Science, EarlyView.The article explores a novel therapeutic strategy for cardiac regeneration by targeting miRNA‐1a and miRNA‐15b. Combinatorial inhibition of miR‐1a and miR‐15b enhances cardiomyocyte proliferation, improves heart function, and reduces fibrosis in myocardial infarction models.
Ting Yuan +16 more
wiley +1 more source
TWIK Complex Expression in Prostate Cancer: Insights into the Biological and Therapeutic Significances of Potassium Ion Channels in Clinical Cancer. [PDF]
Biology (Basel)Alfahed A.
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Advanced Science, EarlyView.NEU1, a key regulator of glycolysis, is markedly upregulated following DOX treatment. This upregulation is attributed to HIF1α’s transcriptional repression, requiring intricate interactions with NRF2. Increased NEU1 facilitates SIRT1 lysosomal degradation, contributing to aberrant glycolytic phenotype and cardiac damage.
Ting Gao +13 more
wiley +1 more source
Digital evolution: Novo Nordisk's shift to ontology-based data management. [PDF]
J Biomed SemanticsTan SZK +11 more
europepmc +1 more source
Reusing an ontology to generate numeral classifiers [PDF]
, 2000 Francis Bond, Kyonghee Paik
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De Novo Reconstruction of 3D Human Facial Images from DNA Sequence
Advanced Science, EarlyView.This study introduces Difface, a novel deep‐learning model for reconstructing 3D facial images only from DNA data. By integrating transformer networks, spiral convolutions, and a diffusion model, Difface directly aligns high‐dimensional SNP data with 3D facial structures.
Mingqi Jiao +11 more
wiley +1 more source