Results 271 to 280 of about 1,266,792 (389)

Special Issue – Agriculture Ontology

Journal of Integrative Agriculture, 2012
Xian-xue MENG
doaj   +1 more source

Building a framework for reproducibility: the case for standardized data reporting and metadata integration in zebrafish research.

Dis Model Mech
Ngu MS, Toro S, Burger A, Ang KC.
europepmc   +1 more source

Box embeddings for extending ontologies: a data-driven and interpretable approach. [PDF]

J Cheminform
Memariani A, Glauer M, Flügel S, Neuhaus F, Hastings J, Mossakowski T.   +5 more
europepmc   +1 more source

Prickle4 Drives Microenvironmental Remodeling and Resistance to Parp Inhibition in IDH‐Mutant Glioma

Advanced Science, EarlyView.
IDH‐mutant gliomas exhibit sensitivity to PARP inhibitors (PARPi) owing to oncometabolite 2‐HG‐induced DNA repair defects. PARPi treatment induces resistance by upregulating Prickle4, which promotes VEGF‐driven angiogenesis. Combining PARPi veliparib with anti‐angiogenic lenvatinib blocks this pathway, causing tumor regression and prolonged survival in
Ju Yang, Hua Yang, Yifan Yuan, Chenyang Zhang, Ziwei Fu, Yanyan Chen, Yinghong Xiong, Shuyu Chen, Kexin Ling, Ying Liu, Jason T. Huse, Bo Chen, Timothy A. Chan, Zengxin Qi, Zhao Zhang, Xiuping Liu, Yuxiang Wang   +16 more
wiley   +1 more source

AgroLD: a knowledge graph for the plant sciences. [PDF]

BMC Genom Data
Pierre L, Bertrand P, Ndomassi T, Yann P, Bill Gates HH, Valentin G, Manuel R.   +6 more
europepmc   +1 more source

From SHIQ and RDF to OWL: the making of a Web Ontology Language

Journal of Web Semantics, 2003
Ian Horrocks, P. Patel-Schneider, F. V. Harmelen   +2 more
semanticscholar   +1 more source

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

Advanced Science, EarlyView.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang, Chaohu Wang, Jun Fan, Zexin Chen, Haoying Yu, Yawen Bai, Tingcheng Zhang, Qianchao Zhu, Yiwen Feng, Peirong Niu, Jiaqian Chen, Liping Yang, Xueying Li, Lei Yu, Songtao Qi, Yi Liu   +15 more
wiley   +1 more source

Frontmatter

Journal of Social Ontology, 2018
Journal of Social Ontology
doaj  

Looking at bacterial cell poles from a liquid-liquid phase separation of intrinsically disordered proteins perspective. [PDF]

Curr Res Struct Biol
Aldadah R, Lekic D, Sabanovic K, Kovalenko B, Adilovic M, Hromic-Jahjefendic A, Uversky VN.   +6 more
europepmc   +1 more source

Pharmacological Microglial Inhibition Remodels the Scar Microenvironment to Support Reticulospinal Circuit Reconstruction After Spinal Cord Injury

Advanced Science, EarlyView.
This study establishes pharmacological microglial inhibition as a therapeutic strategy, demonstrating its capacity to remodel the lesion microenvironment through significant reduction of extracellular matrix deposition. This permissive environmental transformation facilitates robust regeneration of the reticulospinal tract, and reconstructs functional ...
Run Li, Hongyuan Xing, Yifan Shen, Meng Chen, Bowen Lyu, Xiaofeng Yang, Li Sun, Chao Jiang, Jianyu Lv, Xin Ding, Zhongyang Gao, Yue Wang   +11 more
wiley   +1 more source