Results 311 to 320 of about 1,189,057 (413)

A semantic approach to mapping the Provenance Ontology to Basic Formal Ontology. [PDF]

open access: yesSci Data
Prudhomme T   +6 more
europepmc   +1 more source

Deciphering the Metabolic Impact and Clinical Relevance of N‐Glycosylation in Colorectal Cancer through Comprehensive Glycoproteomic Profiling

open access: yesAdvanced Science, EarlyView.
The comprehensive proteomic and N‐glycoproteomic analyses of 45 colorectal cancer tissues with matched normal adjacent tissues identified 7125 intact N‐glycopeptides from 704 glycoproteins. A glycosylation site‐protein function network revealing metabolic dysregulation is constructed and a model differentiating tumors from normal tissues is developed ...
Guobin Liu   +10 more
wiley   +1 more source

Targeted Delivery of α‐ketoglutarate to Macrophages in Bone: A Novel Therapeutic Strategy for Improving Fracture Healing in Type 2 Diabetes

open access: yesAdvanced Science, EarlyView.
The study reveals that glutaminolysis in macrophages is inhibited under type 2 diabetes mellitus (T2DM) conditions, which impedes fracture healing by reducing bone morphogenetic protein 2 (BMP2) production through increased cytosine methylation on the promoter.
Jing Wang   +12 more
wiley   +1 more source

Medical ontology learning framework to investigate daytime impairment in insomnia disorder and treatment effects. [PDF]

open access: yesCommun Med (Lond)
Büsser AJ   +6 more
europepmc   +1 more source

A note on the refinement of ontologies

open access: gold, 2000
Grigoris Antoniou, Athanasios Kehagias
openalex   +1 more source

Genomic and Cis‐Regulatory Basis of a Plastic C3‐C4 Photosynthesis in Eleocharis Baldwinii

open access: yesAdvanced Science, EarlyView.
The sedge Eleocharis baldwinii remarkably switches between C3‐like and C4‐like photosynthesis in response to environmental conditions. Combining gap‐free genome assembly with single‐cell multi‐omics, this study uncovers how subgenome dominance and cell‐specific cis‐regulation enable C4 photosynthesis.
Lu Chen   +11 more
wiley   +1 more source

IR783‐Stabilized Nanodrugs Enhance Anticancer Immune Response by Synergizing Oxidation Therapy and Epigenetic Modulation

open access: yesAdvanced Science, EarlyView.
IR783‐stabilized nanodrugs composed of NIR dye IR783, ROS inducer β‐lapachone, and epigenetic modulator CUDC101 are designed for breast cancer immunotherapy. The nanodrugs can not only promote cancer cell apoptosis through HDAC inhibition‐enhanced oxidation therapy but also reshape the immunosuppressive microenvironment, which provides a novel strategy
Jinzhao Liu   +6 more
wiley   +1 more source

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