Results 211 to 220 of about 43,195 (259)

The critical role of standards for AI in digital pathology: Digital Pathology Association Concept Paper. [PDF]

J Pathol Inform
Chauhan C, Parwani A, Schumacher V, Sebastian M, Bui MM, Lin PC, Blakely S, Fathima S, Gibbs J, Horchner U, Lujan G, Osamura RY, Pantanowitz L, Samboy J, Zioga C, Herrmann M, Yeh J, Oen H, Dash RC, Lennerz JK, Schmid J.   +20 more
europepmc   +1 more source

CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction

Advanced Science, EarlyView.
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma, Jiali Jia, Juncong Lan, Jing Wang, Dan Rao, Lanlan Rao, Weibin Zhang, Dongpeng Wu, Jie Zhang, Gang Wang, Baohua Liu, Ying Ao, Zimei Wang   +12 more
wiley   +1 more source

Identifying Metabolite-Disease Associations via Messaging in Hypergraphs. [PDF]

Metabolites
Xiao F, Ran Y, Li Z.
europepmc   +1 more source

A Bone Marrow–Mimetic Hydrogel Enables Dual‐Phase Hemostasis and Vascularized Osteogenesis for Cranial Defects

Advanced Science, EarlyView.
A biomimetic, fiber‐reinforced hydrogel (FE‐PDA@Fib/Gel‐TG) that enables dual‐phase cranial defect repair. The system provides: instant hemostasis in the early stage, and sustained co‐delivery of pro‐angiogenic and osteogenic signals for synergistic vascularized bone regeneration.
Lingbin Che, Donghong Li, Huan Zhang, Tingting Xu, Juhan Li, Xuanzhou Chen, Louis D. Zhang, Shuguang Wang, Dianwen Song, Dongyong Sha   +9 more
wiley   +1 more source

Towards a digital twin for smart resilient cities: real-time fire and smoke tracking and prediction platform for community awareness (FireCom). [PDF]

Comput Urban Sci
Seong K, Jiao J, Lewis RH, Farahi A, Navrátil P, Casebeer N, Davis B, Jones J, Niyogi D.   +8 more
europepmc   +1 more source

Advancing European Plant Variety Registration: Data‐Driven Insights and Stakeholder Perspectives

Agribusiness, EarlyView.
ABSTRACT Efficient plant variety registration is crucial for fostering innovation in the European Union, yet the current regulatory framework is complex and faces calls for reform. This study provides data‐driven evidence to inform the ongoing legislative debate by employing a mixed‐methods approach.
Sergio Urioste Daza, Ibtissem Taghouti, José María Gil Roig   +2 more
wiley   +1 more source

BabelFSH-a toolkit for an effective HL7 FHIR-based terminology provision. [PDF]

J Biomed Semantics
Wiedekopf J, Ohlsen T, Kock-Schoppenhauer AK, Ingenerf J.   +3 more
europepmc   +1 more source

Autonomous AI‐Driven Design for Skin Product Formulations

Advanced Intelligent Discovery, EarlyView.
This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang, Yongrui Xiao, Chunlin Chen, Dimitrios Tsaoulidis, Kai Yang, Tao Chen   +5 more
wiley   +1 more source

Multi-site, <i>in vivo</i> MRI dataset of brain diffusivity measures before and after harmonization, and atrophy measures following controlled cortical impact in male and female adult rats. [PDF]

Front Neurol
Kislik G, Fox R, Korotcov A, Zhou J, Febo M, Moghadas B, Bibic A, Zou Y, Wan J, Koehler RC, Adebayo T, Burns MP, McCabe JT, Wang KKW, Huie JR, Ferguson AR, Paydar A, Wanner IB, Harris NG, TOP-NT Investigators.   +19 more
europepmc   +1 more source

OXidative Stress PREDictor: A Supervised Learning Approach for Annotating Cellular Oxidative Stress States in Inflammatory Cells

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
OxSpred, an eXtreme‐Gradient‐Boosting‐‐based supervised learning model, accurately annotates oxidative stress in innate immune cells at the single‐cell level, providing interpretable embeddings with significant biological relevance. This innovative tool revolutionizes the understanding of innate immune cell functions during inflammation and enhances ...
Po‐Yuan Chen, Tai‐Ming Ko
wiley   +1 more source