An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi +5 more
wiley +1 more source
OMIT: dynamic, semi-automated ontology development for the microRNA domain. [PDF]
Huang J +10 more
europepmc +1 more source
Auditory–Tactile Congruence for Synthesis of Adaptive Pain Expressions in RoboPatients
In this work, we explore auditory–tactile congruence for synthesizing adaptive vocal pain expressions in robopatients. Using a robopatient platform that integrates vocal pain sounds with palpation forces, we conducted 7680 trials across 20 participants.
Saitarun Nadipineni +4 more
wiley +1 more source
Analysis and Prediction of User Editing Patterns in Ontology Development Projects. [PDF]
Wang H +4 more
europepmc +1 more source
Multimodal Human–Robot Interaction Using Human Pose Estimation and Local Large Language Models
A multimodal human–robot interaction framework integrates human pose estimation (HPE) and a large language model (LLM) for gesture‐ and voice‐based robot control. Speech‐to‐text (STT) enables voice command interpretation, while a safety‐aware arbitration mechanism prioritizes gesture input for rapid intervention.
Nasiru Aboki +2 more
wiley +1 more source
Ontology development and use for cholangiocarcinoma risk factors and predictions: a term enrichment data analysis and machine learning classification. [PDF]
Pengput A, Diehl AD.
europepmc +1 more source
CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao +27 more
wiley +1 more source
Digital Biomarkers of Cytokine Release Syndrome: Scoping Review and Ontology Development of the Role and Relevance of Digital Measures Using a Mixed Methods Approach. [PDF]
Medberry CJ +24 more
europepmc +1 more source
Pancreatic adenocarcinoma (PAAD) remains highly lethal with limited treatment options. This study demonstrates that coixenolide, a bioactive compound from Coix lacryma‐jobi L. and a key component of the clinically approved Kanglaite injection, exhibits enhanced antitumor efficacy in high‐fat diet (HFD)‐induced obese mice bearing PAAD tumors compared to
Kaidi Chen +20 more
wiley +1 more source
Jackalope Plus tool for post-coordination, ontology development, and precise mapping in observational health studies. [PDF]
Trofymenko M +8 more
europepmc +1 more source

