Results 201 to 210 of about 283,563 (261)

VO: The Vaccine Ontology. [PDF]

Sci Data
Zheng J, Lin AY, Huffman A, Masci AM, Racz R, Wu G, Roan K, Ong E, Sarntivijai S, Hu J, Asfaw E, Kahn H, Li X, Zhang X, Monickaraj J, Kosar N, Li J, Manuel W, Abeysinghe R, Rehana H, Bansal B, Pan Y, Guo J, He V, Song J, Seleznev AI, Hur K, He A, Davydov A, Yang Q, Ostropolets A, Vita R, Peters B, Ruttenberg A, Diehl AD, Hoyt CT, Roncaglia P, Huntley RP, Scheuermann RH, Courtot M, Todd T, Sayers S, Chen F, Li X, Yeh FY, Xiang Z, Ozgur A, Whetzel PL, Musen MA, Mungall CJ, Leitner WW, Cui L, Colby LA, Mobley HLT, Athey BD, Omenn GS, Cowell LG, Tao C, Hur J, Smith B, He Y.   +60 more
europepmc   +1 more source

TET1 Inhibition Promotes Therapeutic Sensitivity in TP53‐Mutant GBM by Influencing Genome Fragility and Altering TAMs Biology

Advanced Science, EarlyView.
In TP53mut GBM cells, reduced P53 function is associated with increased TET1 expression. Genetic or pharmacological inhibition of TET1 correlates with genome fragility, including DNA damage, cellular senescence, telomere shortening, and reactive oxygen species accumulation, which may contribute to increased efficacy of antitumor therapy.
Zhuonan Pu, Jinqiu Liu, Yuxuan Deng, Shuyu Hao, Xiaoli Zhang, Mingxu Yang, Chao Guo, Chao Du, Yingdan Chen, Tai Sun, Nan Ji, Zhengping Zhuang, Jie Feng   +12 more
wiley   +1 more source

Enhancing amharic news classification through ontology-based feature fusion and logistic regression. [PDF]

Sci Rep
Taye BG, Desta AB, Alene AY.
europepmc   +1 more source

TRAF6 Lactylation in Glycolytic Macrophages Drives NF‐κB Signaling and M1 Polarization During Orthodontic Tooth Movement

Advanced Science, EarlyView.
Schematic diagram showing compressive stress triggers glycolytic reprogramming and lactate accumulation in macrophages. Lactate mediates TRAF6 lactylation at K171/K180 dual sites, which enhances its K63‐linked ubiquitination to activate the NF‑κB pathway and promote M1 polarization. This cascade drives orthodontic tooth movement (OTM) and alveolar bone
Xinyi He, Guodong Zhao, Yun Hu, Wenya Bai, Hao Tan, Shuai Yuan, Sihan Yang, Ye Zhu, Xiaohui Xu, Leilei Zheng   +9 more
wiley   +1 more source

A Multi-Agent-Based Approach for Semantic Conformance and Interoperability Testing in IoV Environments. [PDF]

Sensors (Basel)
Zerzzari W, Charaf LA, Azzouzi S, Charaf MEH.   +3 more
europepmc   +1 more source

Modern generative large language models in epilepsy care: a scoping review of current applications, challenges, and future directions. [PDF]

Acta Epileptol
Ge S, Sun Y, Wang Q.
europepmc   +1 more source

A semantic FAIRness framework for epidemiological analysis of COVID-19 data in the UAE. [PDF]

Front Public Health
Al Sabbah H, Bani Hani A, Bessadet N, Aremu O.   +3 more
europepmc   +1 more source

A transdisciplinary framework for chronic illness and chronic pain: a sequential qualitative meta-synthesis. [PDF]

Front Public Health
Safavi-Abbasi S, Tasker R, Reyes PM, Doyle B, Dibaj P, Venezia EA.   +5 more
europepmc   +1 more source

Single-cell discovery of mTOR-associated microglial clusters in human mTORopathies

Kalf RS, Scheper M, Horst EET, Anink JJ, Jansen FE, Hecke Wv, Mühlebner A, Vliet EAv, Mills JD, Aronica E.   +9 more
europepmc   +1 more source