Results 221 to 230 of about 1,450,496 (248)

Structuring integration for patient-centered care: a review-informed ontology-driven modular front-end framework for digital health innovation. [PDF]

Front Digit Health
Ambalavanan R, Snead RS, Marczika J, Towett G, Malioukis A, Mbogori-Kairichi M.   +5 more
europepmc   +1 more source

Ubiquitination of ACSL4 by Parkin Suppresses Ferroptosis and Rescues Glucocorticoid‐Induced Bone Loss

Advanced Science, EarlyView.
GCs reduce Parkin, leading to ACSL4 accumulation and PUFA‐phospholipid‐driven ferroptosis in BMSCs, which impairs osteogenesis and promotes adipogenesis, causing GIOP. Parkin restoration (via OE‐Parkin or Parkin‐LNP@DSS6) ubiquitinates and degrades ACSL4, inhibiting ferroptosis, rescuing bone formation, and rescues GIOP bone loss.
Li‐jiang Han, Jian‐sen Miao, Yi‐feng Shi, Yi‐ting Tu, Yu‐zhe Lin, Lin‐Jie Chen, Bing‐hao Lin, Hua‐lin Li, Xuan‐qi Zheng, Hong‐qiang Wu, Hai‐xiao Liu, Lei Yang, Ai‐min Wu, Zhen Lin, Jian Xiao, Gang Zheng, Chen Jin   +16 more
wiley   +1 more source

Understanding data differences across the ENACT federated research network. [PDF]

JAMIA Open
Wang TD, Henderson DW, Weber GM, Morris M, Sadhu EM, Murphy SN, Visweswaran S, Klann JG.   +7 more
europepmc   +1 more source

Cancer-Derived Exosomes: A Cross-Cancer Comparative Analysis of Exosomal Proteins and MicroRNAs. [PDF]

Int J Mol Sci
Kim JH.
europepmc   +1 more source

The Cell Ontology in the age of single-cell omics. [PDF]

Sci Data
Tan SZK, Puig-Barbe A, Goutte-Gattat D, Eastwood C, Aevermann B, Avola A, Balhoff JP, Bayindir IU, Belfiore J, Caron AR, Fischer DS, George N, Gyori BM, Haendel MA, Hoyt CT, Kir H, Lubiana T, Matentzoglu N, Overton JA, Peng B, Peters B, Quardokus EM, Ray PL, Roncaglia P, Rivera AD, Stefancsik R, Teh WK, Toro S, Vasilevsky N, Xu C, Zhang Y, Scheuermann RH, Mungall CJ, Diehl AD, Osumi-Sutherland D.   +34 more
europepmc   +1 more source

FHBMarkerDb: unifying genomic markers and functional annotations for durable FHB resistance in major cereals. [PDF]

Front Plant Sci
Mohapatra A, Singh Y, Sharma D, Mishra DC, Pradhan AK, Jha GK, Singh AK, Singh R, Singh GP, Budhlakoti N, Kumar S.   +10 more
europepmc   +1 more source