Results 41 to 50 of about 166,522,410 (297)

Overcoming Transmission Barriers: A Dual‐Functional Adhesive Hydrogel for Direct Monkeypox Virus Neutralization and Wound Healing

open access: yesAdvanced Science, EarlyView.
MPXV infection leads to persistent viral replication and severe local inflammation, while existing treatments cannot simultaneously remove viruses and repair injured tissue. This study constructs Polymer@mPDA@Gel hydrogel via a two‐step hierarchical assembly method: mPDA anchors photothermal polymers to form antiviral photothermal subunits, which are ...
Ming Zhang   +7 more
wiley   +1 more source

Ferroptosis Suppression by the M6A Reader IGF2BP1 Underlies Gemcitabine Resistance in Pancreatic Ductal Adenocarcinoma

open access: yesAdvanced Science, EarlyView.
IGF2BP1 promotes gemcitabine resistance in pancreatic cancer by stabilizing m6A‐modified FTH1 transcripts and protecting them in stress granules, thereby suppressing ferroptosis. Pharmacological inhibition of IGF2BP1 disrupts this protective pathway, restores ferroptotic sensitivity, and enhances gemcitabine efficacy in resistant tumors.
Ying‐Qin Zhu   +10 more
wiley   +1 more source

Combining lexical and context features for automatic ontology extension

open access: yes, 2020
Background Ontologies are widely used across biology and biomedicine for the annotation of databases. Ontology development is often a manual, time-consuming, and expensive process.
Kafkas, Senay   +3 more
core   +1 more source

Building an Advance Domain Ontology Model of Information Science (OIS) [PDF]

open access: yes, 2014
The paper describes the process of modelling domain knowledge of Information Science (IS) by creating an Ontology of Information Science domain (OIS).
Lu, Joan, Sawsaa, Ahlam
core   +2 more sources

BRIDGING THE GAPS : A PARADIGMATIC INSIGHT INTO PHILOSOPHY OF LAW

open access: yesDiponegoro Law Review, 2016
Paradigm represents a worldview that defines, for its holder, the nature of theworld, the individual's place in it, and the range of possible relationships to thatworld and its parts. It comprises of four main elements, i.e.
Erlyn Indarti
doaj   +1 more source

An Injectable Metal‐Drug Supramolecular Condensate Enables Radiosensitization and Systemic Antitumor Immunity for Post‐Surgical Osteosarcoma Therapy

open access: yesAdvanced Science, EarlyView.
This work designed an injectable metal‐drug supramolecular condensate formed from hafnium ions and alendronate (Hf‐ALN) and loaded with the COX‐2 inhibitor celecoxib (CXB) for synergistic radioimmunotherapy of postoperative osteosarcoma. Mechanistically, upon X‐ray irradiation, Hf enhances radiation energy deposition, ROS generation, and DNA damage ...
Tianhua Xiao   +12 more
wiley   +1 more source

Nomology, Ontology, and Phenomenology of Law and Technology [PDF]

open access: yes, 2007
Tranter, Kieran. (2007). Nomology, Ontology, and Phenomenology of Law and Technology.
Tranter, Kieran
core  

RATIO LEGIS OF SETTING TIME LIMITS FOR JUDGES IN RETURNING DISPUTES IN INDUSTRIAL RELATIONS UNDER ARTICLE 103 LAW NUMBER 2 OF 2004

open access: yesRussian Journal of Agricultural and Socio-Economic Sciences, 2021
This article is results from legal research on setting time limits for judges to decide industrial relations disputes with legal certainty and justice. This study aims to examine and analyze the ratio legis Article 103 of Law Number 2 of 2004.
Yowana I M.A.   +3 more
doaj   +1 more source

AI‐Driven Cancer Multi‐Omics: A Review From the Data Pipeline Perspective

open access: yesAdvanced Intelligent Discovery, EarlyView.
The exponential growth of cancer multi‐omics data brings opportunities and challenges for precision oncology. This review systematically examines AI's role in addressing these challenges, covering generative models, integration architectures, Explainable AI for clinical trust, clinical applications, and key directions for clinical translation.
Shilong Liu, Shunxiang Li, Kun Qian
wiley   +1 more source

Artificial Intelligence for Advanced Functional Materials: Progress and Emerging Frontiers

open access: yesAdvanced Intelligent Systems, EarlyView.
Artificial intelligence is transforming the discovery of functional materials by linking synthesis, characterization, simulation, and design in unified workflows. Advances in machine learning, autonomous experimentation, and foundation models are accelerating innovation across energy, electronics, and biomedicine, while revealing new frontiers for ...
Cristiano Malica   +38 more
wiley   +1 more source

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