Dermatophytes’ identification by Matrix-assisted laser desorption ionization-time of flight mass spectrometry. (MALDI-TOF MS) - the experience of a clinical laboratory [PDF]
, 2019 Objectives: Dermatophytes are a challenging group of fungi that infect the keratinized tissues. The taxonomy of these fungi has changed recently with the reclassification of some species and description of new ones. However, many clinical laboratories
Sabino, R. +3 more
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Global onychomycosis management and the challenges of antifungal stewardship
Journal of Dermatological TreatmentPurpose Onychomycosis, in contrast to other routine superficial dermatophyte infections, is difficult to treat and poor outcomes are not unusual. Few guidelines for onychomycosis management have been published, and these vary considerably from region to ...
Aditya K. Gupta +9 more
doaj +1 more source
Clinical Diagnostic Accuracy of Onychomycosis: A Multispecialty Comparison Study
Dermatology Research and Practice, 2018 Although onychomycosis can be diagnosed clinically, many guidelines still recommend pathologic confirmation of the diagnosis prior to initiation of systemic treatment. We retrospectively reviewed results from 541 toenail clippings (160 by dermatologists,
David G. Li +5 more
doaj +1 more source
Which oral antifungal is best for toenail onychomycosis? [PDF]
, 2007 Terbinafine, 250 mg taken daily for 12 weeks, is the best regimen for toenail onychomycosis due to better clinical and mycologic cure rates, tolerability, and cost effectiveness (strength of recommendation [SOR]: A, meta-analyses)
Hinojosa, Jose R., Hitchcock, Kristin
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Mycoses, Volume 68, Issue 6, June 2025.ABSTRACT Background Trichophyton mentagrophytes species complex comprises dermatophytes responsible for common superficial fungal infections affecting keratinised tissues. Recent shifts in taxonomy and increasing antifungal resistance—necessitate an updated understanding of this fungal complex.
Settanan Plangsiri +2 more
wiley +1 more source
Ultrasonographic characterization of the nails in patients with psoriasis and onychomycosis
The Egyptian Journal of Radiology and Nuclear Medicine, 2015 Objective: The study aimed at assessment of ultrasound (US) in diagnosing nail psoriasis and onychomycosis. Methods: One hundred subjects were included: the psoriatic patients group (n = 25), the onychomycosis patients group (n = 25) and the control ...
Shaymaa Muhammad Ally Essayed +3 more
doaj +1 more source
Automated Detection of Systematic Off-label Drug Use in Free Text of Electronic Medical Records. [PDF]
, 2013 Off-label use of a drug occurs when it is used in a manner that deviates from its FDA label. Studies estimate that 21% of prescriptions are off-label, with only 27% of those uses supported by evidence of safety and efficacy.
Jung, Kenneth +2 more
core +2 more sources
Efinaconazole in the treatment of onychomycosis
Infection and Drug Resistance, 2015 Efinaconazole 10% topical solution is a new triazole recently approved for the treatment of onychomycosis. It inhibits fungal lanosterol 14α-demethylase in the ergosterol biosynthesis pathway, has potent antifungal activity against dermatophytes, as well as activity against Candida spp.
Shari R. Lipner, Richard K. Scher
openaire +4 more sources
بررسی فراوانی اونيکومايکوزيس ناشی از قارچ های مخمری در ناخن های ديستروفيک بيماران مراجعه کننده به بيمارستان رازی 90-1389 [PDF]
, 2012 زمينه و هدف : مخمرها يکی از شايع‌ترين عوامل ايجادکنندۀ اونيکومايکوزيس می‌باشند. در کشورهايی مثل ايران، عربستان، ايتاليا و اسپانيا مخمرها بيشترين فراوانی گزارش شده را دارند.
احمدی, فرزانه +6 more
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Tratamiento de la onicomicosis con itraconazol y terbinafina : revisión sistemática [PDF]
, 2019 [Resumen] INTRODUCCIÓN La onicomicosis es la enfermedad más común en las uñas y representa el 30% de las micosis cutáneas. En la actualidad, los antifúngicos más utilizados para el tratamiento de la onicomicosis son los orales, aunque no se conoce cuál ...
García Mariño, Jennifer
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