Results 291 to 300 of about 246,958 (342)

Optimizing <i>in vitro</i> maturation of oocytes with nitric oxide-loaded microbubbles. [PDF]

open access: yesFront Cell Dev Biol
Qiu L   +8 more
europepmc   +1 more source

Lactate Promotes the Second Cell Fate Decision in Blastocysts by Prompting Primitive Endoderm Formation Through an Intercellular Positive Feedback Loop That Couples Paracrine FGF Signalling

open access: yesCell Proliferation, EarlyView.
Paracrine FGF4 from EPI precursor cells promotes lactate synthesis within PrE precursor cells, while the increased lactate in turn stimulates FGF‐ERK signalling via lactate shuttling. The increased lactate in PrE precursor cells directly promotes PrE formation by elevating the level of histone lactylation. ABSTRACT Lactate has been widely recognised as
Xiao Hu   +9 more
wiley   +1 more source

Transcriptional Changes in Cumulus Cells During In Vitro Maturation of Human Oocytes. [PDF]

open access: yesMol Reprod Dev
Cadenas J   +7 more
europepmc   +1 more source

kcnb1 loss of function in zebrafish causes neurodevelopmental and epileptic disorders associated with γ‐aminobutyric acid dysregulation

open access: yesEpilepsia, EarlyView.
Abstract Objective KCNB1 encodes an α‐subunit of the delayed‐rectifier voltage‐dependent potassium channel Kv2.1. De novo pathogenic variants of KCNB1 have been linked to developmental and epileptic encephalopathies (DEEs), diagnosed in early childhood and sharing limited treatment options.
Lauralee Robichon   +7 more
wiley   +1 more source

Cryopreservation and transplantation of ovarian tissue as post-cancer tissue therapy and an activator of oogenesis. [PDF]

open access: yesJ Ovarian Res
Isachenko V   +10 more
europepmc   +1 more source

Functions of Bidirectional Sex Change and Simultaneously Hermaphroditic Phase Gonads in the Monogamous Goby Lubricogobius exiguus

open access: yesEthology, EarlyView.
Many fishes can change their sex. The remarkable example, Lubricogobius exiguus, is a goby that can undergo bidirectional sex change with hermaphroditic gonads, containing both developed ovaries and testes (simultaneously hermaphroditic phase gonad). Based on field observations, we demonstrate that the goby experiences frequent social changes, such as ...
Takumi Oyama   +2 more
wiley   +1 more source

Transcriptomic Profile of Early Antral Follicles: Predictive Somatic Gene Markers of Oocyte Maturation Outcome. [PDF]

open access: yesCells
Peserico A   +9 more
europepmc   +1 more source

The good parent: Emerging themes and gender convergence in narrating fertility choices

open access: yesFamily Relations, EarlyView.
ABSTRACT Objective This study investigates the themes behind men's and women's ex‐post narratives on fertility intentions and the fertility gap, analyzing reflections shared after fertility‐related events or decisions. Background The lack of children stems from either a deliberate choice or the fertility gap, the discrepancy between intended and ...
Alessandra Minello, Concetta Russo
wiley   +1 more source

Editorial: Aging and the oocyte

open access: yesFrontiers in Endocrinology
Yun-Yao Luo   +5 more
openaire   +3 more sources

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