Results 141 to 150 of about 8,151 (329)

Blastocyst freeze-all strategy versus fresh transfer in anonymous oocyte donation cycles [PDF]

open access: bronze, 2018
Nicole Doyle   +7 more
openalex   +1 more source

KCNJ4 variants disrupt inward‐rectifier potassium channel function and cause refractory epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Epilepsy is a common neurological disorder with a strong genetic basis, most frequently arising from ion channel dysfunction. Although multiple inwardly rectifying potassium (Kir) channels have been implicated in epileptogenesis, the contribution of KCNJ4, which encodes the Kir2.3 channel, has not previously been established in human
Hu Pan   +20 more
wiley   +1 more source

P-329 Oocyte donation outcomes in endometriosis patients with multiple IVF failures [PDF]

open access: bronze, 2023
Rami Hachem   +8 more
openalex   +1 more source

Add‐on treatment with vinpocetine reduces seizure frequency and improves comorbidities in patients with loss‐of‐function γ‐aminobutyric acid type A receptor variants

open access: yesEpilepsia, EarlyView.
Abstract Objective The semisynthetic compound vinpocetine has gained attention as a potential precision medicine for developmental and epileptic encephalopathies caused by loss‐of‐function (LoF) variants in γ‐aminobutyric acid type A (GABAA) receptor genes. As a positive allosteric modulator of GABAA receptors, case reports suggest that vinpocetine can
Cathrine E. Gjerulfsen   +15 more
wiley   +1 more source

Precision therapies for genetic epilepsies in 2025: Promises and pitfalls

open access: yesEpilepsia Open, EarlyView.
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang   +3 more
wiley   +1 more source

Impact of donor mare and stallion identity on the likelihood of pregnancy after transfer of in vitro produced embryos

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background The success of in vitro embryo production (IVEP) is influenced by donor mare and stallion. Objectives To determine whether donor mare and stallion influence the pregnancy rate after transfer of in vitro produced (IVP) blastocysts and to identify factors influencing the likelihood of obtaining one or more pregnancies from a single ...
M. Papas   +11 more
wiley   +1 more source

Age, embryo donor status, and insemination with chilled semen all predispose to persistent breeding‐induced endometritis in warmblood mares

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Persistent breeding‐induced endometritis (PBIE) is a common reason for mares failing to establish pregnancy. Objective To examine the hypothesis that advancing mare age and embryo donor status predispose to PBIE and compromise fertility.
Tom Stout   +3 more
wiley   +1 more source

Development and psychometric evaluation of a questionnaire addressing the psychosocial needs of oocyte recipient women

open access: yesBMC Psychiatry
Background The social pressures of using a third party in infertility treatment impose a high psychosocial burden, particularly on women, increasing their psychosocial needs whose identification is imperative to provide comprehensive wellness programs in
Shohre Ghelich-Khani   +3 more
doaj   +1 more source

Unlocking new horizons in egg donation: clinical and logistical benefits of double ovarian stimulation

open access: yesF&S Reports
Objective: To study the clinical and logistical benefits of double ovarian stimulation (DuoStim) in egg donation Design: Prospective and observational study Subjects: Sixty healthy egg donors aged 18–35, all with regular menstrual cycles, normal ...
María Cruz, Ph.D.   +2 more
doaj   +1 more source

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