Results 181 to 190 of about 5,426 (249)
Andrology, EarlyView.ABSTRACT Background Oligoasthenoteratozoospermia (OAT), characterized by reduced sperm count, impaired motility, and abnormal morphology, is a major cause of male infertility with substantial genetic heterogeneity. However, the underlying genetic etiology remains unresolved in a large proportion of affected individuals.
Jianteng Zhou +8 more
wiley +1 more source
Sperm Head–Tail Coupling Apparatus Diversity and Common Themes Among Species
Andrology, EarlyView.ABSTRACT Background A stable connection between the sperm head (containing the nucleus and acrosome) and tail (containing the axoneme, mitochondrial sheath, and periaxonemal structures) is critical for fertility. This connection is mediated by a series of nuclear, cytoplasmic, and centriole components that make up the head–tail coupling apparatus (HTCA)
Danielle B. Buglak +2 more
wiley +1 more source
Andrology, EarlyView.ABSTRACT Background Sperm mitochondrial DNA copy number is an emerging marker of male fertility, with elevated mtDNAcn associated with poor semen quality across various populations. Sperm DNA methylation has also been previously demonstrated to be negatively correlated with semen parameters in IVF cohorts.
Savni Sawant +7 more
wiley +1 more source
Andrology, EarlyView.ABSTRACT Background Selecting high‐quality spermatozoa with optimal nuclear integrity is a crucial step in assisted reproductive technologies (ART). While density gradient centrifugation (DGC) is widely used, the associated centrifugation steps may induce cell stress, potentially damaging sperm DNA.
Simone Palini +7 more
wiley +1 more source
ZAN, IZUMO1, and TMEM95 Protein Domains Identify the Physiological Status of the Sperm
Andrology, EarlyView.ABSTRACT Background Infertility is a growing concern, which has led to an increase in the use of assisted reproductive techniques, involving in vitro sperm capacitation. Nonetheless, the optimal capacitation time remains a matter of debate, and it is unknown whether it has an impact on the localization of key membrane proteins.
Miranda Hernández‐Falcó +5 more
wiley +1 more source
When two diseases collide: Endometriosis as a risk factor for severe pelvic inflammatory disease
Acta Obstetricia et Gynecologica Scandinavica, EarlyView.Endometriosis is associated with a more severe clinical course of pelvic inflammatory disease in hospitalized patients, including higher rates of antibiotic treatment failure, longer hospital stay, and increased need for surgical intervention. Abstract Introduction Our objective was to compare the severity of pelvic inflammatory disease (PID) in ...
Marta Camacho +7 more
wiley +1 more source
Acta Zoologica, EarlyView.ABSTRACT Weapons are morphological structures used by animals in various contexts, especially in intra‐specific contests and visual displays. In snapping shrimps of the genus Alpheus, particularly the monogamous species Alpheus brasileiro, both sexes bear enlarged chelipeds, potentially conferring advantages in mate competition or territorial defence ...
Leonardo Moreira +3 more
wiley +1 more source
The Embryonic Development of the Cotylean Polyclad Phrikoceros jannetae
Acta Zoologica, EarlyView.ABSTRACT Polyclads exhibit distinct developmental modes ranging from direct to indirect development, with several transitional stages also recognised. The existence of an indirect developmental mode in polyclads with a planktonic life history stage in the form of a free‐swimming larva is unique among all free‐living flatworms and makes polyclads a ...
Mehrez Gammoudi +6 more
wiley +1 more source
Compartmentalisation in cAMP signalling: A phase separation perspective
British Journal of Pharmacology, EarlyView.Cells rely on precise spatiotemporal control of signalling pathways to ensure functional specificity. The compartmentalisation of cyclic AMP (cAMP) and protein kinase A (PKA) signalling enables distinct cellular responses within a crowded cytoplasmic space.
Milda Folkmanaite, Manuela Zaccolo
wiley +1 more source