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Current Opinion in Obstetrics and Gynecology, 2002
In contrast to conventional assisted reproduction techniques in which metaphase II oocytes are retrieved for fertilization in vitro, during the in-vitro maturation of oocytes, immature germinal vesicle stage oocytes are retrieved and matured in the laboratory before fertilization and embryo transfer.
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In contrast to conventional assisted reproduction techniques in which metaphase II oocytes are retrieved for fertilization in vitro, during the in-vitro maturation of oocytes, immature germinal vesicle stage oocytes are retrieved and matured in the laboratory before fertilization and embryo transfer.
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Maturation of Oocytes in Vitro
Annual Review of Animal Biosciences, 2016Only a fraction of oocytes present in the ovaries at birth are ever ovulated during the lifetime of a female mammal. In vitro maturation (IVM) offers the possibility to exploit what is a largely untapped biological resource. Although IVM is used routinely for the in vitro production of embryos in domestic species, especially cattle, its clinical use ...
Patrick, Lonergan, Trudee, Fair
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Ultrastructure of Maturing Human Oocytes
Annals of the New York Academy of Sciences, 1985The material for study consisted of 41 nonatretic oocytes obtained at follicular aspiration in women in whom ovarian stimulation had been carried out. Collected oocytes were clinically classified as preovulatory and immature by the amount, dispersion, and viscosity of cumulus‐corona cells surrounding the oocytes.
P, Sundström +3 more
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The Regulation of Oocyte Maturation
2003Publisher Summary This chapter reviews the signaling networks bringing about oocyte maturation of different species, emphasizing significant variability among animals at almost every level. The final development of fertilization competence of an oocyte—responsible for making it a fertilizable egg—usually occurs during the process of meiosis and is ...
Ekaterina, Voronina, Gary M, Wessel
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Mouse Oocyte Maturation: Meiotic Checkpoints
Experimental Cell Research, 1995Mouse oocytes at different stages of maturation were fused together and the ensuing cell cycle events were analyzed with the objective of identifying checkpoints in meiosis. Fusion of maturing oocytes just undergoing germinal vesicle breakdown (GVBD) induces PCC (premature chromosome condensation) but no spindle formation in immature (GV) partner ...
J, Fulka, R M, Moor, J, Fulka
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Oocyte Maturation in Amphibians
1985This chapter presents a complex picture of the regulation of oocyte maturation. The events that have been identified can be expressed temporally on a relative time scale, as shown in Figure 8. A major question that lies ahead concerns which of these events is causal for subsequent events and for GVBD.
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In Vitro Maturation of Oocytes
Seminars in Reproductive Medicine, 2005In vitro maturation of oocytes is a safe and effective treatment offered in some fertility centers for assisted reproduction, where immature oocytes are retrieved from unstimulated ovaries. Therefore, the procedure avoids ovarian stimulation with expensive gonadotropins, side effects of the medications, and risks such as ovarian hyperstimulation ...
G Durga, Rao, Seang Lin, Tan
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Meiotic maturation in mollusc oocytes
Seminars in Cell & Developmental Biology, 1998Molluscs, annelids and other lower invertebrates belonging to the protostome group exhibit special features in their ionic regulation of meiotic maturation and in their molecular control of metaphase arrest. These oocytes proceed from prophase I upon fertilization or hormonal stimulation and then either complete meiotic maturation or secondarily arrest
P, Colas, F, Dubé
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Regulation of amphibian oocyte maturation
Cell Differentiation, 1985Xenopus oocyte maturation is a model system for studying the control of cell proliferation and the regulation of the cell cycle. Addition of progesterone or insulin to oocytes releases a G2 block and stimulates progression through meiosis to an unfertilized egg.
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Clinics in endocrinology and metabolism, 1986
The preovulatory surge of gonadotropins induces within the mature Graafian follicle a series of changes culminating in the release of a fertilizable ovum. These include resumption of the meiotic division, a process held in abeyance from a short time after birth, and the progression of the oocyte from the dictyate stage to the metaphase of the second ...
A, Tsafriri, S H, Pomerantz
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The preovulatory surge of gonadotropins induces within the mature Graafian follicle a series of changes culminating in the release of a fertilizable ovum. These include resumption of the meiotic division, a process held in abeyance from a short time after birth, and the progression of the oocyte from the dictyate stage to the metaphase of the second ...
A, Tsafriri, S H, Pomerantz
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