Results 41 to 50 of about 280,910 (369)
Genome-wide methylation profile of mitochondrial DNA across bovine preimplantation development
Epigenetics, 2023 This study characterized variations in the methylation profile of mitochondrial DNA (mtDNA) during initial bovine embryo development and correlated the presence of methylation with mtDNA transcription.
Camila Bruna de Lima +3 more
doaj +1 more source
Ultrafast imaging of cell elasticity with optical microelastography [PDF]
PNAS January 18, 2018. 201713395, 2018 Elasticity is a fundamental cellular property that is related to the anatomy, functionality and pathological state of cells and tissues. However, current techniques based on cell deformation, atomic force microscopy or Brillouin scattering are rather slow and do not always accurately represent cell elasticity.
arxiv +1 more source
Digital multiplexed mRNA analysis of functionally important genes in single human oocytes and correlation of changes in transcript levels with oocyte protein expression [PDF]
, 2014 Objective To investigate functionally important transcripts in single human oocytes with the use of NanoString technology and determine whether observed differences are biologically meaningful.
Homer, H, Riris, S, Webster, P
core +1 more source
NLRP2 controls age-associated maternal fertility [PDF]
, 2016 Nucleotide-binding domain and leucine-rich repeat (NLR) proteins are well-known for their key roles in the immune system. Ectopically expressed NLRP2 in immortalized cell lines assembles an inflammasome and inhibits activation of the proinflammatory ...
Agostini +24 more
core +2 more sources
Journal of Animal Reproduction and Biotechnology, 2017 This study was conducted to investigate the effects of alpha-lipoic acid (aLA) as an antioxidant that decrease the reactive oxygen species (ROS) in bovine embryonic development.
Bahia M. S. Hassan +4 more
doaj +1 more source
Frontiers in Endocrinology, 2023 Infertility and menstrual abnormalities in endometriosis patients are frequently caused by aberrant follicular growth or a reduced ovarian reserve. Endometriosis typically does not directly harm the oocyte, but rather inhibits the function of granulosa ...
Weisen Fan +4 more
doaj +1 more source
LSD1 is essential for oocyte meiotic progression by regulating CDC25B expression in mice [PDF]
, 2015 Mammalian oocytes are arrested at prophase I until puberty when hormonal signals induce the resumption of meiosis I and progression to meiosis II.
Chen, T +8 more
core +1 more source
Inferring simple but precise quantitative models of human oocyte and early embryo development [PDF]
arXiv, 2021 Macroscopic, phenomenological models have proven useful as concise framings of our understandings in fields from statistical physics to economics to biology. Constructing a phenomenological model for development would provide a framework for understanding the complicated, regulatory nature of oogenesis and embryogenesis.
arxiv
Mouse versus Rat: Profound Differences in Meiotic Regulation at the Level of the Isolated Oocyte [PDF]
, 2011 Cumulus cell-enclosed oocytes (CEO), denuded oocytes (DO), or dissected follicles were obtained 44–48 hr after priming immature mice (20–23 days old) with 5 IU or immature rats (25–27 days old) with 12.5 IU of equine chorionic gonadotropin, and exposed ...
Biggers +61 more
core +2 more sources
Animals, 2022 In vitro maturation (IVM) of mammalian oocytes, which influences subsequent in vitro development of embryos, is affected by the macromolecule content in culture media for the success of oocyte maturation competence, in which the cytoplasmic and nuclear ...
Uğur Şen +5 more
doaj +1 more source