Results 41 to 50 of about 420,620 (395)

Integrative single-cell analysis of transcriptome, DNA methylome and chromatin accessibility in mouse oocytes

open access: yesCell Research, 2018
Oocyte growth is a key step in forming mature eggs that are ready to be fertilized. The states and modifications of chromatin represent critical sources of information for this process.
Chan Gu   +4 more
semanticscholar   +1 more source

Genome-wide methylation profile of mitochondrial DNA across bovine preimplantation development

open access: yesEpigenetics, 2023
This study characterized variations in the methylation profile of mitochondrial DNA (mtDNA) during initial bovine embryo development and correlated the presence of methylation with mtDNA transcription.
Camila Bruna de Lima   +3 more
doaj   +1 more source

Fine morphological assessment of quality of human mature oocytes after slow freezing or vitrification with a closed device: a comparative analysis [PDF]

open access: yes, 2014
BACKGROUND: Human mature oocytes are very susceptible to cryodamage. Several reports demonstrated that vitrification might preserve oocyte better than slow freezing. However, this is still controversial.
A. Borini   +7 more
core   +2 more sources

Digital multiplexed mRNA analysis of functionally important genes in single human oocytes and correlation of changes in transcript levels with oocyte protein expression [PDF]

open access: yes, 2014
Objective To investigate functionally important transcripts in single human oocytes with the use of NanoString technology and determine whether observed differences are biologically meaningful.
Homer, H, Riris, S, Webster, P
core   +1 more source

Effect of Alpha Lipoic Acid as an Antioxidant Supplement during In Vitro Maturation Medium on Bovine Embryonic Development

open access: yesJournal of Animal Reproduction and Biotechnology, 2017
This study was conducted to investigate the effects of alpha-lipoic acid (aLA) as an antioxidant that decrease the reactive oxygen species (ROS) in bovine embryonic development.
Bahia M. S. Hassan   +4 more
doaj   +1 more source

Decreased oocyte quality in patients with endometriosis is closely related to abnormal granulosa cells

open access: yesFrontiers in Endocrinology, 2023
Infertility and menstrual abnormalities in endometriosis patients are frequently caused by aberrant follicular growth or a reduced ovarian reserve. Endometriosis typically does not directly harm the oocyte, but rather inhibits the function of granulosa ...
Weisen Fan   +4 more
doaj   +1 more source

NLRP2 controls age-associated maternal fertility [PDF]

open access: yes, 2016
Nucleotide-binding domain and leucine-rich repeat (NLR) proteins are well-known for their key roles in the immune system. Ectopically expressed NLRP2 in immortalized cell lines assembles an inflammasome and inhibits activation of the proinflammatory ...
Agostini   +24 more
core   +2 more sources

Maturation of Oocytes in Vitro.

open access: yesAnnual Review of Animal Biosciences, 2016
Only a fraction of oocytes present in the ovaries at birth are ever ovulated during the lifetime of a female mammal. In vitro maturation (IVM) offers the possibility to exploit what is a largely untapped biological resource.
P. Lonergan, T. Fair
semanticscholar   +1 more source

LSD1 is essential for oocyte meiotic progression by regulating CDC25B expression in mice [PDF]

open access: yes, 2015
Mammalian oocytes are arrested at prophase I until puberty when hormonal signals induce the resumption of meiosis I and progression to meiosis II.
Chen, T   +8 more
core   +1 more source

Macromolecules Influence Cellular Competence and Expression Level of IGFs Genes in Bovine Oocytes In Vitro

open access: yesAnimals, 2022
In vitro maturation (IVM) of mammalian oocytes, which influences subsequent in vitro development of embryos, is affected by the macromolecule content in culture media for the success of oocyte maturation competence, in which the cytoplasmic and nuclear ...
Uğur Şen   +5 more
doaj   +1 more source

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