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Integration of Bioengineered Tools in Assisted Reproductive Technologies
A conceptual illustration depicting the collaboration between a medical professional (right) and a scientist (left). Their connection highlights the integration of scientific research and clinical practice. This representation underscores the role of emerging technologies in bridging fundamental research with applied reproductive healthcare.
Aslı Ak+3 more
wiley +1 more source
Mitochondria are the most abundant organelles in mammalian oocytes and early embryos. The central role of mitochondria in the establishment of developmental competence of oocytes and early embryos come out from basic research in experimental models and ...
Manuel Belli
doaj +1 more source
Effect of Vitamin E on Oocytes Apoptosis in nicotine-treated Mice [PDF]
Objective(s): Cigarette and nicotine enhances embryogenesis, fertility, pregnancy loss and ultrastructure alterations of oocyte. This study was performed to determine the effect of daily supplementation of vitamin E on oocytes apoptosis in nicotine ...
Asadi, E.+2 more
core +1 more source
Perturbing Microtubule Integrity Blocks AMP-Activated Protein Kinase-Induced Meiotic Resumption in Cultured Mouse Oocytes [PDF]
The oocyte meiotic spindle is comprised of microtubules (MT) that bind chromatin and regulate both metaphase plate formation and karyokinesis during meiotic maturation; however, little information is known about their role in meiosis reinitiation.
Downs, Stephen, Ya, Ru
core +2 more sources
Retrieval of Mouse Oocytes [PDF]
To date, only a few studies have reported successful manipulations of Peromyscus embryogenesis or reproductive biology. Together with the Peromyscus Genetic Stock Center (http://stkctr.biol.sc.edu), we are characterizing the salient differences needed to develop this system. A primary goal has been to optimize oocyte/early embryo retrieval.
Paul B. Vrana, Amanda R. Duselis
openaire +3 more sources
ACLY is vital for early embryo development. IGF‐1 activates AKT to phosphorylate ACLY, driving its nuclear localization and recruitment of HATs (P300/HAT1), boosting acetyl‐CoA production and histone acetylation for transcriptional activation. Conversely, ACLY deficiency (via knockdown, knockout, or AKT inhibition) reduces nuclear acetyl‐CoA, disrupts ...
Yerong Ma+18 more
wiley +1 more source
Oocyte maturation is a critical step in the completion of female gametogenesis in the ovary; thus, for subsequent fertilization and embryogenesis. Vitrification of embryo also has been shown to be closely associated with oocyte maturation. To improve the
Peipei Zhang+12 more
doaj +1 more source
Laser microdissection as a new approach to prefertilization genetic diagnosis [PDF]
The genetic status of oocytes can be determined by polar body (PB) analysis. Following PB extraction, a genetic evaluation is performed. As each PB contains the complementary genetic material of the oocyte, PB analysis reveals information about its ...
Buchholz, Tina+2 more
core +1 more source
Gentle Label‐Free Nonlinear Optical Imaging Relaxes Linear‐Absorption‐Mediated Triplet
The phototoxicity in nonlinear optical microscopy arises mainly from linear absorption of intrinsic biomolecules rather than nonlinear absorption. This mechanism is supported by a reproducible phototoxicity assay based on widely available chicken breast.
Geng Wang+4 more
wiley +1 more source
Etude de la fécondité du silure Africain Heterobranchus bidorsalis (Geoffroy Saint-Hilaire, 1840) en conditions d'élevage [PDF]
Artificial Reproduction and Fecundity of the African Catfish Heterobranchus bidorsalis (Geoffroy Saint- Hilaire, 1840). Through the artificial reproduction of Heterobranchus bidorsalis, fecundity of females, characteristics of oocytes and larvae after ...
Alla, YL.+3 more
doaj