Results 191 to 200 of about 204,815 (342)

Novel Non-Invasive Treatment for Canine Corneal Ulcers: Application of New Extracellular Matrix-Based Sticky Sealants. [PDF]

Vet Ophthalmol
Yang SJ, Jang JH, Park JY, Jang J, Kim JY.   +4 more
europepmc   +1 more source

MG53 Coordinates Macrophage Polarization and Neuroimmune Coupling to Promote Corneal Nerve Regeneration via the MPEG1–MVP–STAT6 Axis

Advanced Science, EarlyView.
Corneal nerve regeneration is critical to corneal wound healing processes. The current study reveals a novel role of MG53 in promoting corneal nerve regeneration after alkali induced injury. Mechanistically, MG53 enters macrophages via its receptor, MPEG1, promotes MVP K63 ubiquitination, and triggers STAT6 induced repair‐related genes expression ...
Peng Chen, Zhentao Zhang, Lilian Sakai, Yanping Xu, Luxi Zhang, Han Ye, William Sollenberger, Takahide Ikeda, Zhiyu Yan, Keerthika Sathish, Usman Alizai, Haitao Wen, Timothy M. Pawlik, Heather L. Chandler, Hua Zhu   +14 more
wiley   +1 more source

Degrees of Epistemic Opacity

This article discusses the notions of ‘epistemic opacity’ — referred to here as ‘weak epistemic opacity’ — and ‘essential epistemic opacity’ originally proposed by Paul Humphreys, and defends the idea that epistemic opacity, in general, should be taken ...
San Pedro, Iñaki
core  

Cytokeratin-Positive Pleomorphic Chest Wall Sarcoma Mimicking MPNST: A Case Report. [PDF]

Cancer Manag Res
Aldakak MA, Nasra AB, Ahmad R, Alhallaq H, Assoud K, Chaban H.   +5 more
europepmc   +1 more source

Brain and Liver Dual‐Targeting Oridonin Nanoparticles to Enhance Aβ Clearance for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
We developed a nanoparticle named OAF, which simultaneously targeted to both the brain and liver via the transferrin receptor 1 (TfR1) receptor, promoting lipoprotein receptor‐related protein 1 (LRP1) expression to enhance amyloid‐beta (Aβ) clearance. In AD mice model, OAF significantly reduced Aβ deposition and cognitive impairment, while a mitigating
Wenshuai Gong, Wenting Hui, Sai Qiao, Qifeng Ji, Miao Liu, Bangle Zhang, Daozhou Liu, Yumei Wu, Siyuan Zhou   +8 more
wiley   +1 more source

The Financial Structure of Startup Firms: The Role of Assets, Information, and Entrepreneur Characteristics [PDF]

Using the Kauffman Firm Survey, we examine how characteristics of a startup's assets, information about the startup, and entrepreneur attributes relate to financial structure at inception.
Catherine Mann, Paroma Sanyal
core  

Prevalence and severity of molar incisor hypomineralization among children in Madinah, Saudi Arabia: A school-based cross-sectional study. [PDF]

BMC Oral Health
Alqadi SF, Algarni AA, Tarawah RA, Sharbib SH, Alhazmi RT, Alaydaa RM, Baghlaf K, Sabbagh HJ.   +7 more
europepmc   +1 more source

Multi‐Omics Profiling Reveals Immunomodulatory and Pro‐Regenerative Effects of a Graphene Oxide–Collagen Scaffold in Massive Rotator Cuff Tears

Advanced Science, EarlyView.
A graphene oxide/collagen scaffold is developed for chronic massive rotator cuff tear repair. The scaffold improves compressive stability, supports reparative mesenchymal differentiation, and modulates the immune microenvironment. In chronic MRCT models, it reduces muscle degeneration, enhances tendon–bone regeneration, and improves functional recovery,
Renwen Wan, Yechuan Deng, Zixin Hu, Yanwei He, Xinting Feng, Jun Ma, Yisheng Chen, Zhijie Zhao, Jie Mei, Zhiheng Lin, Wei Luo, Zhengyuan Fang, Zhufeng Hu, Kunlun Feng, Xinrong Li, Dan Wu, Bowen Han, James Hoi po Hui, Xuanyong Liu, Chen Chen, Gang Chen, Shiyi Chen, Nirong Bao, Jiajun Qiu, Zhiwen Luo   +24 more
wiley   +1 more source

Femtosecond laser-assisted cataract surgery versus conventional phacoemulsification surgery: visual outcomes with presbyopia-correcting intraocular lens. [PDF]

Front Med (Lausanne)
Xiao C, Peng R, Zheng Z, He H, Li Y, Hu Z.   +5 more
europepmc   +1 more source

Ethical Precision in Nanoscale Brain Interfacing

Advanced Science, EarlyView.
As brain interfaces approach the nanoscale, precision no longer only measures—it knows, predicts, and potentially reshapes the mind. This work argues that traditional ethics fails under such conditions and proposes a shift toward continuous, operation‐based governance using the recovery–discovery framework to track, constrain, and responsibly steer ...
Guilherme Wood
wiley   +1 more source