Results 141 to 150 of about 16,824,143 (312)
Der Nationale Open-Access-Kontaktpunkt OA2020-DE
o-bib. Das offene Bibliotheksjournal, 2018 Die Open-Access-Bewegung hat in den letzten 15 Jahren zahlreiche Initiativen und Ansätze hervorgebracht, die zu bemerkenswerten Fortschritten in der freien Verfügbarkeit von wissenschaftlichen Publikationen geführt haben.
Alexandra Jobmann
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Information Research: An International Electronic JournalIntroduction. The information professions encompass a range of interconnected disciplines that contribute to the effective creation, processing, management, dissemination, and preservation of information and knowledge in diverse formats and contexts ...
Suliman Hawamdeh +2 more
doaj +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source
Open Access. Chapter 6 of Scholarly Communication for Librarians. [PDF]
, 2008 In-depth overview of open access, covering definitions (open access publishing, open access archives, gratis and libre, open access works versus open access processes), major statements and declarations, types of open access, major initiatives, trends ...
Morrison, Heather
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source