Results 71 to 80 of about 434,684 (281)
From the DEAL engine room — an interview with Bernhard Mittermaier
Library Ideas, 2017 For more than a year there is one topic that has kept the German research community in suspense: the DEAL with the three dominating scholarly publishers Elsevier, Springer Nature and Wiley. The hoped-for deal is a Germany-wide contract, which in addition
Bernhard Mittermaier
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Aus dem DEAL-Maschinenraum — ein Gespräch mit Bernhard Mittermaier
Library Ideas, 2017 Ein Thema hält die deutsche Wissenschaft seit über einem Jahr in Atem: der DEAL mit den drei dominierenden Wissenschaftsverlagen Elsevier, Springer Nature und Wiley.
Bernhard Mittermaier
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o-bib. Das offene Bibliotheksjournal, 2020 Mit der Etablierung von Open Access als Standardmodell des wissenschaftlichen Publizierens verlagert sich der Fokus von Subskriptions- auf Publikationskosten. Die zuverlässige und vollständige Erfassung dieser Kosten stellt eine große Herausforderung für
Claudia Frick, Christian Kaier
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PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Empirical Study and Response Strategies of Open Access Transformation in Chinese University Libraries [PDF]
Nongye tushu qingbao xuebao[Purpose/Significance] With the advancement of open science, the signing of transformative open access agreements will have a profound and long-term impact on the acquisition of library information resources.
Jing GUO, Yihua ZHANG, Yaqi SHEN, Haiyan SONG
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Herausforderungen Der Open-Access-Transformation
, 2016 Folien zu einem am 8. November 2016 gehaltenen Vortrag auf Einladung von GESIS – Leibniz-Institut für Sozialwissenschaften Das Open-Access-Paradigma bezeichnet den freien, ungehinderten Zugriff auf die Ergebnisse wissenschaftlicher Arbeit.
openaire +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Science Tracking über Transformationsverträge und Wissenschaftsplattformen
kommunikation@gesellschaftDer Text untersucht einige Aspekte von Science Tracking, verstanden als die systematische und großflächige digitale Überwachung von Wissenschaft und Wissenschaftler:innen durch ehemalige Großverlage, die als Oligopol den Publikationsmarkt dominieren.
Yuliya Fadeeva
doaj +1 more source