Results 131 to 140 of about 1,575,452 (352)
Hybrid Varieties for Organic Cereals? Prospects and acceptance of hybrid breeding for organic production [PDF]
Hybrid breeding utilizes the advantages characterizing F1 plants in a targeted manner: Vigour, uniformity, and a combination of all dominant traits of the parental lines.
Arncken, Christine, Dierauer, Hansueli
core
PICALM::MLLT10 translocated leukemia
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
The Growing Importance of Secondary Market Activities for Open-end Real Estate Fund Shares in Germany [PDF]
Philipp Gerlach, Raimond Maurer
openalex +1 more source
Sanitation and Hygiene Behaviour Change at Scale: Understanding Slippage [PDF]
As sanitation and hygiene programmes mature, the challenge shifts from bringing communities to ODF status to sustaining this status. In this context, many programmes are confronted with the issue of slippage.
Carolien van der Voorden +2 more
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Silver Dreams Fund Learning and Evaluation Contract: Final report June 2014 [PDF]
This is a summary of the Final Report which presents the findings of the evaluation of the Big Lottery Fund's Silver Dreams Fund conducted by Ecorys.The Silver Dreams Fund was a £10 million programme which sought to address the gaps in provision by ...
Louise Scott +4 more
core
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
The growing importance of secondary market activities for open-end real estate fund shares in Germany [PDF]
Philipp Gerlach, Raimond Maurer
openalex +1 more source
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source

