Results 51 to 60 of about 15,636 (294)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Performance Comparison of PWM Schemes of Dual-inverter FED Five-phase Motor Drives
The dual-inverter fed open-end winding configuration can be categorized as a new breed of multi-level converters. The structure is simple and offers a lot of advantages.
I Nyoman Wahyu Satiawan +3 more
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
This work presents the control strategies for the configuration involving an open-end winding induction motor (OW-IM) fed by dual two-level inverters, which can realize the controllable power sharing between two isolated power sources without using the ...
Yi-Fan Jia +6 more
doaj +1 more source
This paper proposes an advanced discontinuous pulse-width modulation (DPWM) scheme for a dual inverter to reduce switching loss. A dual inverter is used to drive an open-end winding interior permanent magnet synchronous motor (OEW-IPMSM).
Hyung-Woo Lee +2 more
doaj +1 more source
Matrix Converter Based Open-end Winding Drives [PDF]
University of Minnesota Ph.D. dissertation. August 2015. Major: Electrical/Computer Engineering. Advisor: Ned Mohan. 1 computer file (PDF); xiii, 172 pages.A significant portion of all electric power generated is consumed by electric motors employed in ...
Tewari, Saurabh
core
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Ac Five-Phase Drive Systems Based on Cascade Converters and Open-End Winding Five Phase Machine
This paper presents two AC machine drive systems based on three-phase to five-phase ACAC converters and open-end winding five-phase machine. The drive systems are suitable for applications in which high power, performance and reliability are required ...
Cursino B. Jacobina +4 more
doaj +1 more source
Novel End-Winding Hybrid Flux Machine
This paper presents a novel motor topology, called the End-Winding Flux Machine (EWM), which explores the potential function of end-windings in rotating electric machines.
Zhang, Xiaochen +15 more
core +1 more source

