Results 91 to 100 of about 156,017 (326)

Antiviral treatment for Bell's palsy (idiopathic facial paralysis) [PDF]

open access: yes, 2009
BACKGROUND: Antiviral agents against herpes simplex virus are widely used in the treatment of idiopathic facial paralysis (Bell's palsy), but their effectiveness is uncertain. Significant morbidity can be associated with severe cases.
Abiko   +47 more
core   +3 more sources

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani   +8 more
wiley   +1 more source

Open-label placebo treatment does not enhance cognitive abilities in healthy volunteers

open access: yesScientific Reports, 2023
AbstractThe use of so-called ‘smart drugs’ such as modafinil to improve cognitive performance has recently attracted considerable attention. However, their side effects have limited user enthusiasm. Open-label placebo (OLP) treatment, i.e., inert treatments that are openly disclosed to individuals as having no active pharmacological ingredient, has ...
Helena Hartmann   +6 more
openaire   +6 more sources

Development and piloting of a food-based intervention to increase vitamin E intake in pregnant women in a randomised controlled trial [PDF]

open access: yes, 2016
Acknowledgement This study was funded by the University of Aberdeen and an unrestricted grant from Baxters Food Group Ltd.
Clark, Julia   +5 more
core   +1 more source

Applying an Ethical Lens to the Treatment of People With Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The practice of neurology requires an understanding of clinical ethics for decision‐making. In multiple sclerosis (MS) care, there are a wide range of ethical considerations that may arise. These involve shared decision‐making around selection of a disease‐modifying therapy (DMT), risks and benefits of well‐studied medications in comparison to
Methma Udawatta, Farrah J. Mateen
wiley   +1 more source

Cognitive facilitation following intentional odor exposure [PDF]

open access: yes, 2011
This paper reviews evidence that, in addition to incidental olfactory pollutants, intentional odor delivery can impact cognitive operations both positively and negatively.
Aggleton   +98 more
core   +4 more sources

Improvements in Health‐Related Quality of Life With Treat‐to‐Target Urate‐Lowering Therapy in Gout: A Post Hoc Analysis of a Randomized Multicenter Trial

open access: yesArthritis Care &Research, EarlyView.
Objective Although treat‐to‐target urate‐lowering therapy (ULT) is endorsed as best practice in gout management, limited data exist on its impact on health‐related quality of life (HRQoL). We assessed the impact of treat‐to‐target ULT on HRQoL among participants receiving protocolized gout care, identifying factors associated with HRQoL and HRQoL ...
Austin Barry   +16 more
wiley   +1 more source

The Role of Rituals in Open-Label Placebo Effects

open access: yes, 2023
Placebos have been shown to generate beneficial effects on mental health and well-being even when they are administered openly, without deception. However, research on open-label placebos (OLPs) is limited and there is still some uncertainty regarding how OLP effects can be created consistently.
openaire   +2 more sources

Heterogeneity of Rheumatoid Arthritis–Associated Interstitial Lung Disease by Longitudinal Forced Vital Capacity Trajectory and Associations With Disease Outcomes

open access: yesArthritis Care &Research, EarlyView.
Objective We aimed to identify unique disease trajectories within rheumatoid arthritis–associated interstitial lung disease (RA‐ILD) based on longitudinal forced vital capacity (FVC) values and their associated clinical outcomes. Methods We performed a cohort study of RA‐ILD within the Veterans Health Administration from 1999 to 2021.
Bryant R. England   +9 more
wiley   +1 more source

Open-Label Placebo Treatment: Outcome Expectations and General Acceptance in the Lay Population

open access: yesInternational Journal of Behavioral Medicine, 2020
Most physicians sometimes apply therapies without specific active ingredients. Although patients seem to judge such placebo treatments as acceptable under certain circumstances, deception is still an ethical problem. Open-label placebos (OLPs) might be a
J. Haas, W. Rief, B. Doering
semanticscholar   +1 more source

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