Results 101 to 110 of about 53,082 (303)

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi   +5 more
wiley   +1 more source

Management plan of geological hazard threats in the fault zone of adjacent open-pit mines

open access: yesMeitan kexue jishu
In the development of large-scale open-pit coal fields in China, there are often several Coal companies entering the same coal field, and each Coal company is a main body of development, mining coal resources in the state-allocated strip area, and ...
Guangwei LIU   +5 more
doaj   +1 more source

A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley   +1 more source

A New Machine-Learning Prediction Model for Slope Deformation of an Open-Pit Mine: An Evaluation of Field Data

open access: yesEnergies, 2019
Effective monitoring of the slope deformation of an open-pit mine is essential for preventing catastrophic collapses. It is a challenging task to accurately predict slope deformation.
Sunwen Du   +5 more
doaj   +1 more source

Cognitive Behavioral Therapy for Youth With Childhood‐Onset Lupus: A Randomized Clinical Trial

open access: yesArthritis Care &Research, EarlyView.
Objective Our objective was to determine the feasibility and acceptability of the Treatment and Education Approach for Childhood‐Onset Lupus (TEACH), a six‐session cognitive behavioral intervention addressing depressive, fatigue, and pain symptoms, delivered remotely to individual youth with lupus by a trained interventionist.
Natoshia R. Cunningham   +29 more
wiley   +1 more source

Mycophenolate Mofetil Treatment Reduces the Risk of Treatment Escalation Due to Vascular Complications in Limited Cutaneous Systemic Sclerosis: Emulation of a Target Trial From the Italian Rheumatology Society SPRING Registry

open access: yesArthritis Care &Research, EarlyView.
Objective Mycophenolate mofetil (MMF) use in limited cutaneous systemic sclerosis (lcSSc) is relatively uncommon because of the lower fibrotic burden and the predominance of vascular complications. In vitro observations and clinical data from transplanted patients suggest a protective effect of MMF on endothelial function.
Enrico De Lorenzis   +77 more
wiley   +1 more source

PHOTOGRAMMETRIC SURVEY OF OPEN PIT MINE

open access: yesBOOK OF PROCEEDINGS XIII (2018), 2017
<p>There is a geodetic department in Ugljevik Coal Mine. In addition to all tasks(expropriation, geometry control of existing engineering objects, monitoring oflandslides, etc.), the primary task of the geodetic service is to calculate the volume of theexcavated masses on a surface mine during a certain period of time.
Miodrag Regodić   +3 more
openaire   +2 more sources

Analysis of the impact of rock joint cracks on blastability of burnt rock in Xinjiang open pit coal mines

open access: yesScientific Reports
In response to the problems of developed rock fractures and unsatisfactory bench blasting effects in open-pit coal mines in Xinjiang, China, By using on-site research, theoretical analysis, numerical simulation and other methods, the main influencing ...
Ziling Song, Yu Wen, Zhengzhao Jia
doaj   +1 more source

Effect of Implementing a Dashboard With or Without a Best Practice Alert on HLA‐B*58:01 Testing Rates Among Allopurinol Users at VA Medical Centers

open access: yesArthritis Care &Research, EarlyView.
Objective The American College of Rheumatology recommends HLA‐B*58:01 allele testing before the initiation of allopurinol, specifically among Asian and African American/Black patients, due to their increased risk for severe hypersensitivity reactions. However, testing rates remain low at many health care facilities.
Abimbola Fadairo‐Azinge   +6 more
wiley   +1 more source

High Health Care Utilization Preceding Diagnosis With Juvenile Idiopathic Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective Although early diagnosis improves long‐term outcomes, patients with juvenile idiopathic arthritis (JIA) often experience prolonged, circuitous paths to diagnosis. To inform diagnostic improvement, we sought to characterize health care utilization in the year preceding diagnosis. Methods We identified 10,021 patients with an incident diagnosis
Anna Costello   +5 more
wiley   +1 more source

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