Results 181 to 190 of about 2,806,784 (213)

An Open-Source Analysis of Cardiomyopathy Using Machine Learning and Electrocardiograms. [PDF]

Diagnostics (Basel)
Altintepe A, Rustemli A, Vazifeh AR, Fleischer JW.   +3 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

HERMES: an open-source mining tool for open-access literature. [PDF]

Bioinform Adv
Charest J, Priselac K, Reischer GH, Farnleitner AH, Mach RL, Mach-Aigner AR.   +5 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Bionicohand: a collaborative, open-source myoelectric prosthetic hand designed with and for its user. [PDF]

J Neuroeng Rehabil
Pissard-Gibollet R, Butin C, Huchet N, Boutard H, Cariou S, Corbel Y, Dreano C, Forest J, Fromentin C, Van Haaren A, Braillon C, Azevedo Coste C.   +11 more
europepmc   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Spoti-find: a novel, open-source void spot assay image analysis tool. [PDF]

Am J Physiol Renal Physiol
Hardy CC, Sheehan S, Mawe S, Sebasco N, Ricke W, Mahoney M, Korstanje R.   +6 more
europepmc   +1 more source

Protocol for inferring mechanical stresses in tissues using ForSys, an open-source Python tool. [PDF]

STAR Protoc
Borges A, Miranda-Rodríguez JR, Ceccarelli AS, Ventura G, Sedzinski J, López-Schier H, Chara O.   +6 more
europepmc   +1 more source

Sensitivity and concordance study of an open source EPID-based linear accelerator test suite. [PDF]

J Appl Clin Med Phys
Critchfield LC, Knill CS, Durussel E, Mikell JK, Barnes M, Pillainayagam M, Donahue WP, Lim SB, DeMarco JJ, Perez M, Gupta N, Al-Hallaq H, Popple RA, Irrer J, Moran JM.   +14 more
europepmc   +1 more source

DNAi: an open-source AI tool for unbiased DNA fiber analysis. [PDF]

Nucleic Acids Res
Playout C, Mehrjoo Y, Duval R, Boucher MC, Costantino S, Wurtele H.   +5 more
europepmc   +1 more source