Results 161 to 170 of about 18,672,321 (342)
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Assessment and Support Measures of Academic Journals in the National Open Access Platform AccessON
This study aims to assess the maturity of Korean open access (OA) journals using the OA infrastructure provided by the Korea Institute of Science and Technology Information, and develop necessary strategies for future improvement.
Hyekyong Hwang +3 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
In this paper, we propose STPLF, which stands for the short-term forecasting of locational marginal price components, including the forecasting of non-conforming hourly net loads.
Matin Farhoumandi +7 more
doaj +1 more source
Recommendations for the Open Access Transition
The following “Recommendations for Open Access transition” have been compiled by the Ad-hoc workgroup “Open-Access-Gold” in the priority initiative “Digital Information” of the Alliance of Science Organizations in Germany .
Hanig, Kristina +10 more
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Workshop at Open Repositories 2014, Helsinki, Finland, June 9-13, 2014Workshops and TutorialsThe Open Access Button is a browser-based tool that aims to show the global effects of research paywalls and help users get access to the research they need ...
Andrews, Penny CS
core
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

