Results 211 to 220 of about 15,990,185 (371)

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Multiplikator*innen für eine offene Wissenschaft

o-bib. Das offene Bibliotheksjournal, 2022
Sabrina Stockhusen, Linda Martin
doaj   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Open access atmospheric pressure chemical ionization Mass spectrometry for routine sample analysis

, 1995
Lester C. E. Taylor, Robert L. Johnson, Roberto Raso   +2 more
openalex   +1 more source

Open Access To Broadband Networks: A Case Study Of The AOL/Time Warner Merger [PDF]

, 2001
Daniel L. Rubinfeld, Hal J. Singer
openalex   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Goldener, Grüner und „Anderer“ Weg zu Open Access: Statistiken für Österreich

Mitteilungen der Vereinigung Österreichischer Bibliothekarinnen und Bibliothekare, 2015
Archambault et al. veröffentlichten 2014 einen Report, der die Open-Access-(OA)-Raten für Publikationen der Jahre 2008–2013 aus allen Ländern des Europäischen Forschungsraums (ERA) sowie für Brasilien, Kanada, Japan und die USA enthält.
Nora Schmidt
doaj  

On "Open Access" Publishers Who Oppose Open Access Self-Archiving Mandates

, 2007
The online age has made powerful new benefits for research possible, but these benefits entail a profound conflict of interest between (1) what is best for the research journal publishing industry and (2) what is best for research, researchers ...
Harnad, Stevan
core  

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Open-access paediatric echocardiography: changing role and referral patterns to a consultant-led service in a tertiary referral centre.

, 1996
A. T. Tybulewicz, Michael L. Rigby, A N Redington   +2 more
openalex   +1 more source