Results 71 to 80 of about 15,990,185 (371)

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

The weakest link – workflows in open access agreements: the experience of the Vienna University Library and recommendations for future negotiations

Insights: The UKSG Journal, 2018
In recent years open access (OA) publishing agreements have left a lasting impact on several aspects of the research life cycle, and on the manner in which institutions work with publishers and researchers to support the transition to OA.
Rita Pinhasi, Guido Blechl, Brigitte Kromp, Bernhard Schubert   +3 more
doaj   +1 more source

The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery

ACS Central Science, 2019
Despite rapid evolution in the area of microbial natural products chemistry, there is currently no open access database containing all microbially produced natural product structures. Lack of availability of these data is preventing the implementation of
J. A. V. Santen, G. Jacob, A. Singh, Victor Aniebok, Marcy J. Balunas, Derek Bunsko, F. C. Neto, F. C. Neto, F. C. Neto, Laia Castaño-Espriu, Chen Chang, Trevor N. Clark, Jessica C. Little, David A Delgadillo, P. Dorrestein, Katherine R. Duncan, Joseph M. Egan, Melissa M Galey, F. Haeckl, Alex Hua, Alison H. Hughes, Dasha Iskakova, Aswad S. Khadilkar, Jung‐Ho Lee, Sanghoon Lee, Nicole LeGrow, Dennis Y. Liu, Jocelyn M Macho, C. McCaughey, M. Medema, R. Neupane, T. J. O'Donnell, Jasmine S. Paula, Laura M. Sanchez, A. F. Shaikh, S. Soldatou, Barbara R. Terlouw, T. Tran, Tuan A. Tran, Mercia C. Valentine, J. J. Hooft, Duy A. Vo, Mingxun Wang, Darryl M. Wilson, Katherine E. Zink, Roger G. Linington   +45 more
semanticscholar   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

FEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Understanding healthcare providers’ preferred attributes of pediatric pneumococcal conjugate vaccines in the United States

Human Vaccines & Immunotherapeutics
As higher-valent pneumococcal conjugate vaccines (PCVs) become available for pediatric populations in the US, it is important to understand healthcare provider (HCP) preferences for and acceptability of PCVs.
Salini Mohanty, Jui-Hua Tsai, Ning Ning, Ana Martinez, Rishi P. Verma, Marieke Heisen, Jessica Weaver, Kristen A. Feemster, Bianca Chun, Thomas W. Weiss, Jordana K Schmier   +10 more
doaj   +1 more source

Towards Open Access [PDF]

Molecular Cancer, 2005
The National Institutes of Health has issued a new policy for open access to all NIH-funded research, whereby NIH grantees are strongly encouraged to deposit their complete manuscripts and supplementary material to an Internet repository, thereby enabling the rapid dissemination of research results and the long-term archiving of scientific literature ...
Christian Schmidt, Christian Schmidt, Chhaya Das, Gregory C. Ippolito, Philip W. Tucker   +4 more
openaire   +4 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Open-Access and The Cupola [PDF]

, 2013
I am currently working to develop The Cupola, Gettysburg College’s open-access compliant institutional repository. That’s a mouthful! What, exactly, is an open-access compliant institutional repository?
Hill, John C.
core   +1 more source

Critical Care's move to fund open access [PDF]

, 2003
SCOPUS: ed.jinfo:eu-repo/semantics ...
Slade, Elizabeth, Tamber, Pritpal S, Vincent, Jean-Louis   +2 more
core   +2 more sources

Opening Access to Research [PDF]

The Economic Journal, 2015
Traditionally, the scholarly journal market operates so that research institutions are charged high prices and the wider public is often excluded altogether, while authors can usually publish for free and commercial publishers enjoy high pro…ts. Two forms of open access regulation can mitigate these problems: (i) direct price regulation of the form ...
openaire   +5 more sources