Results 151 to 160 of about 1,079,458 (300)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

AOASG and Creative Commons Australia response to the Australian Government National Innovation and Science Agenda and review of research policy and funding arrangements

open access: yes, 2015
The Australasian Open Access Support Group and Creative Commons Australia  welcome the new initiatives in the government’s National Innovation and Science Agenda.
Australasian Open Access Support Group   +1 more
core  

Open Access Publication in Value in Health [PDF]

open access: yesValue in Health, 2016
Michael, Drummond, C Daniel, Mullins
openaire   +2 more sources

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

The Influence of Open Access on Institutional Scientific Research Output in MENA Countries: A Comparative Analysis

open access: yesSAGE Open
The release of scientific research has substantial consequences for both the research and the institution in which it was carried out. The selection of publishing methods for scientific articles, such as journal type, quartile, indexed databases, and ...
Marwan Al-Raeei, Chadi Azmeh
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Modern versus Traditional Policies in Publication of Scientific Articles in Health Domain

open access: yesمدیریت اطلاعات سلامت, 2012
• Until recent time, the publishers of scientific articles owned the intellectual and economic copyright by providing the facilities for reviewing and publications.‌ Nevertheless, based on the recent technological advancements, a modern policy called ...
Mohsen Rezaeian
doaj  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

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